Anti CYP11A1 pAb (ATL-HPA016436 w/enhanced validation)

Atlas Antibodies

SKU: ATL-HPA016436-25

• 

Protein Description: cytochrome P450, family 11, subfamily A, polypeptide 1
Gene Name: CYP11A1
Alternative Gene Name: CYP11A, P450SCC
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032323: 73%, ENSRNOG00000008074: 59%
Entrez Gene ID: 1583
Uniprot ID: P05108
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: RSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAA
• Gene Sequence: RSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAA
• Gene ID - Mouse: ENSMUSG00000032323
• Gene ID - Rat: ENSRNOG00000008074
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti CYP11A1 pAb (ATL-HPA016436 w/enhanced validation) – 7 Found

Gaudriault, Pierre; Mazaud-Guittot, Séverine; Lavoué, Vincent; Coiffec, Isabelle; Lesné, Laurianne; Dejucq-Rainsford, Nathalie; Scholze, Martin; Kortenkamp, Andreas; Jégou, Bernard. Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants. Environmental Health Perspectives. 2017;125(8):087004. 

Melau, Cecilie; Nielsen, John Erik; Frederiksen, Hanne; Kilcoyne, Karen; Perlman, Signe; Lundvall, Lene; Langhoff Thuesen, Lea; Juul Hare, Kristine; Andersson, Anna-Maria; Mitchell, Rod T; Juul, Anders; Jørgensen, Anne. Characterization of Human Adrenal Steroidogenesis During Fetal Development. The Journal Of Clinical Endocrinology And Metabolism. 2019;104(5):1802-1812. 

Arboleda, Valerie A; Lee, Hane; Parnaik, Rahul; Fleming, Alice; Banerjee, Abhik; Ferraz-de-Souza, Bruno; Délot, Emmanuèle C; Rodriguez-Fernandez, Imilce A; Braslavsky, Debora; Bergadá, Ignacio; Dell'Angelica, Esteban C; Nelson, Stanley F; Martinez-Agosto, Julian A; Achermann, John C; Vilain, Eric. Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nature Genetics. 2012;44(7):788-92. 

Harpelunde Poulsen, K; Nielsen, J E; Frederiksen, H; Melau, C; Juul Hare, K; Langhoff Thuesen, L; Perlman, S; Lundvall, L; Mitchell, R T; Juul, A; Rajpert-De Meyts, E; Jørgensen, A. Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes. Human Reproduction (Oxford, England). 2019;34(11):2228-2243. 

Hutka, Marsida; Kadam, Prashant; Van Saen, Dorien; Homer, Natalie Z M; Onofre, Jaime; Wallace, W Hamish B; Smith, Lee B; Stukenborg, Jan-Bernd; Goossens, Ellen; Mitchell, Rod T. Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment. Cancers. 2020;12(10) 

Lecante, Laetitia L; Leverrier-Penna, Sabrina; Gicquel, Thomas; Giton, Frank; Costet, Nathalie; Desdoits-Lethimonier, Christèle; Lesné, Laurianne; Fromenty, Bernard; Lavoué, Vincent; Rolland, Antoine D; Mazaud-Guittot, Séverine. Acetaminophen (APAP, Paracetamol) Interferes With the First Trimester Human Fetal Ovary Development in an Ex Vivo Model. The Journal Of Clinical Endocrinology And Metabolism. 2022;107(6):1647-1661. 

Lundgaard Riis, Malene; Matilionyte, Gabriele; Nielsen, John E; Melau, Cecilie; Greenald, David; Juul Hare, Kristine; Langhoff Thuesen, Lea; Dreisler, Eva; Aaboe, Kasper; Brenøe, Pia Tutein; Andersson, Anna-Maria; Albrethsen, Jakob; Frederiksen, Hanne; Rajpert-De Meyts, Ewa; Juul, Anders; Mitchell, Rod T; Jørgensen, Anne. Identification of a window of androgen sensitivity for somatic cell function in human fetal testis cultured ex vivo. Bmc Medicine. 2022;20(1):399.