Anti CXCR4 mAb (Clone 2F10)

CUSABIO

Catalog No.:
CSB-RA569311A0HU-50
Immunofluorescence staining of Hela Cells with CSB-RA569311A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Product Specifications
Application IF, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 2F10)

Documents & Links for Anti CXCR4 mAb (Clone 2F10)
Datasheet Anti CXCR4 mAb (Clone 2F10) Datasheet

Documents & Links for Anti CXCR4 mAb (Clone 2F10)
Datasheet Anti CXCR4 mAb (Clone 2F10) Datasheet
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