Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA011880-25
  • Immunohistochemistry analysis in human epididymis and skeletal muscle tissues using Anti-CUL4B antibody. Corresponding CUL4B RNA-seq data are presented for the same tissues.
  • Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
  • Western blot analysis in human cell line U-251 MG.
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Protein Description: cullin 4B
Gene Name: CUL4B
Alternative Gene Name:
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000031095: 84%, ENSRNOG00000002585: 85%
Entrez Gene ID: 8450
Uniprot ID: Q13620
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Immunogen GDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATS
Gene Sequence GDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATS
Gene ID - Mouse ENSMUSG00000031095
Gene ID - Rat ENSRNOG00000002585
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation)
Datasheet Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation)
Datasheet Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation)



Citations for Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation) – 5 Found
Chen, Chun-Yu; Yu, I-Shing; Pai, Chen-Hsueh; Lin, Chien-Yu; Lin, Shu-Rung; Chen, You-Tzung; Lin, Shu-Wha. Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells. Plos One. 14(7):e0219221.  PubMed
Li, Jing; Zhang, Yi; Sun, Jing; Chen, Leyuan; Gou, Wenfeng; Chen, Chi-Wei; Zhou, Yuan; Li, Zhuqing; Chan, David W; Huang, Ruili; Pei, Huadong; Zheng, Wei; Li, Yiliang; Xia, Menghang; Zhu, Wenge. Discovery and characterization of potent And-1 inhibitors for cancer treatment. Clinical And Translational Medicine. 2021;11(12):e627.  PubMed
Lu, Guang; Yi, Juan; Gubas, Andrea; Wang, Ya-Ting; Wu, Yihua; Ren, Yi; Wu, Man; Shi, Yin; Ouyang, Chenxi; Tan, Hayden Weng Siong; Wang, Tianru; Wang, Liming; Yang, Nai-Di; Deng, Shuo; Xia, Dajing; Chen, Ruey-Hwa; Tooze, Sharon A; Shen, Han-Ming. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation. Autophagy. 2019;15(11):1917-1934.  PubMed
Dou, Hao; Duan, Yuyao; Zhang, Xiaohui; Yu, Qian; Di, Qian; Song, Yu; Li, Peishan; Gong, Yaoqin. Aryl hydrocarbon receptor (AhR) regulates adipocyte differentiation by assembling CRL4B ubiquitin ligase to target PPARγ for proteasomal degradation. The Journal Of Biological Chemistry. 2019;294(48):18504-18515.  PubMed
Meerang, Mayura; Kreienbühl, Jessica; Orlowski, Vanessa; Müller, Seraina L C; Kirschner, Michaela B; Opitz, Isabelle. Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma. Cancers. 2020;12(11)  PubMed