Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA011880-25

Protein Description: cullin 4B
Gene Name: CUL4B
Alternative Gene Name:
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000031095: 84%, ENSRNOG00000002585: 85%
Entrez Gene ID: 8450
Uniprot ID: Q13620
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: GDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATS
• Gene Sequence: GDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATS
• Gene ID - Mouse: ENSMUSG00000031095
• Gene ID - Rat: ENSRNOG00000002585
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti CUL4B pAb (ATL-HPA011880 w/enhanced validation) – 5 Found

Chen, Chun-Yu; Yu, I-Shing; Pai, Chen-Hsueh; Lin, Chien-Yu; Lin, Shu-Rung; Chen, You-Tzung; Lin, Shu-Wha. Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells. Plos One. 14(7):e0219221. 

Li, Jing; Zhang, Yi; Sun, Jing; Chen, Leyuan; Gou, Wenfeng; Chen, Chi-Wei; Zhou, Yuan; Li, Zhuqing; Chan, David W; Huang, Ruili; Pei, Huadong; Zheng, Wei; Li, Yiliang; Xia, Menghang; Zhu, Wenge. Discovery and characterization of potent And-1 inhibitors for cancer treatment. Clinical And Translational Medicine. 2021;11(12):e627. 

Lu, Guang; Yi, Juan; Gubas, Andrea; Wang, Ya-Ting; Wu, Yihua; Ren, Yi; Wu, Man; Shi, Yin; Ouyang, Chenxi; Tan, Hayden Weng Siong; Wang, Tianru; Wang, Liming; Yang, Nai-Di; Deng, Shuo; Xia, Dajing; Chen, Ruey-Hwa; Tooze, Sharon A; Shen, Han-Ming. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation. Autophagy. 2019;15(11):1917-1934. 

Dou, Hao; Duan, Yuyao; Zhang, Xiaohui; Yu, Qian; Di, Qian; Song, Yu; Li, Peishan; Gong, Yaoqin. Aryl hydrocarbon receptor (AhR) regulates adipocyte differentiation by assembling CRL4B ubiquitin ligase to target PPARγ for proteasomal degradation. The Journal Of Biological Chemistry. 2019;294(48):18504-18515. 

Meerang, Mayura; Kreienbühl, Jessica; Orlowski, Vanessa; Müller, Seraina L C; Kirschner, Michaela B; Opitz, Isabelle. Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma. Cancers. 2020;12(11)