Anti Condensin-2 Complex Subunit H2 (CAP-H2) mAb (Clone 5F2G4)

Cosmo Bio

Catalog No.: CAC-CEC-038

Background

CAP-H2 is regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture.INI1/BAF47/SNF5 is a core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal.

Application

Western blotting, 1/1,000 to 1/5,000
Immunocytochemistry, 1/500
Immunohistochemistry, 1/100 to 1/500

Antigen/Source	CAP-H2 (Condensin II subunit)
Host	Rat
Immunogen	Human
Reacts with	Human/Monkey
Clone	5F2G4
Isotype	IgG2a
Applications	Western Blot/Immunocytochemistry (cell)/Immunoprecipitation
Preservative	0.05% NaN3 in LIQ
Storage	-70C

References

1) Wood et al. (2010) Nat. Rev. Genet. 11:391-404.

Product Specifications

• Application: IP, ICC, WB, IF
• Reactivity: Mouse, Human
• Clonality: Monoclonal (Clone No.: 5F2G4)
• Host: Rat