Anti CERS2 pAb (ATL-HPA027262)

Atlas Antibodies

SKU: ATL-HPA027262-25

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Protein Description: ceramide synthase 2
Gene Name: CERS2
Alternative Gene Name: FLJ10243, LASS2, SP260
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000015714: 95%, ENSRNOG00000021138: 95%
Entrez Gene ID: 29956
Uniprot ID: Q96G23
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: TPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVARWFRRRRNQDRPSLLKKFREA
• Gene Sequence: TPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVARWFRRRRNQDRPSLLKKFREA
• Gene ID - Mouse: ENSMUSG00000015714
• Gene ID - Rat: ENSRNOG00000021138
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti CERS2 pAb (ATL-HPA027262) – 4 Found

Pathak, Divya; Mehendale, Neelay; Singh, Shubham; Mallik, Roop; Kamat, Siddhesh S. Lipidomics Suggests a New Role for Ceramide Synthase in Phagocytosis. Acs Chemical Biology. 2018;13(8):2280-2287. 

Lee, Wing-Kee; Maaß, Michelle; Quach, Amy; Poscic, Nataliya; Prangley, Holly; Pallott, Erin-Claire; Kim, Jiyoon L; Pierce, Jason S; Ogretmen, Besim; Futerman, Anthony H; Thévenod, Frank. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. The Journal Of Biological Chemistry. 2022;298(2):101492. 

Spassieva, Stefka D; Ji, Xiaojie; Liu, Ye; Gable, Kenneth; Bielawski, Jacek; Dunn, Teresa M; Bieberich, Erhard; Zhao, Lihong. Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2016;113(21):5928-33. 

Yang, Bin; Hu, Meiyan; Fu, Yue; Sun, Di; Zheng, Wenxin; Liao, Hong; Zhang, Zhenbo; Chen, Xiong. LASS2 mediates Nrf2-driven progestin resistance in endometrial cancer. American Journal Of Translational Research. 13(3):1280-1289.