Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is most stringently associated with, but certainly not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (γδ) Τ cells and activated CD8+ T cells, as well as on dendritic cells.[5] NCAM has been implicated as having a role in cell–cell adhesion,[6] neurite outgrowth, synaptic plasticity, and learning and memory. During hematopoiesis, CD56 is the prototypic marker of NK cells, also present on subset of CD4+ T cells and CD8+ T cells. [from: Wikipedia contributors. (2019, May 24). Neural cell adhesion molecule. In Wikipedia, The Free Encyclopedia. Retrieved 16:41, June 4, 2019, from https://en.wikipedia.org/w/index.php?title=Neural_cell_adhesion_molecule&oldid=898602503]
References:
1) Koike A., Uematsu Y., Bonkobara M., Yamaguchi T., Washizu T., Arai T. (2007) 144th Annual Meeting of Japanese Society of Veterinary Science, I-39.
2) Uematsu Y, Yamaguchi T, Koike A, Yagihara H, Hasegawa D, Matsuki N, Ono K, Washizu T, Arai T, Bonkobara M. (2008) Generation of Monoclonal Antibody against Canine Neural-Cell Adhesion Molecule. Journal of Veterinary Medical Science. 70(8):845-847.
Product Specifications
Application
WB
Reactivity
Dog
Clonality
Monoclonal (Clone No.: K9BYU)
Host
Mouse
Documents & Links for Anti Canine Neural Cell Adhesion Molecule 1 (NCAM1/CD56) mAb (Clone K9BYU)
