Anti CD2AP pAb (ATL-HPA003326 w/enhanced validation)

Atlas Antibodies

SKU: ATL-HPA003326-25

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Protein Description: CD2-associated protein
Gene Name: CD2AP
Alternative Gene Name: CMS
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000061665: 81%, ENSRNOG00000011987: 82%
Entrez Gene ID: 23607
Uniprot ID: Q9Y5K6
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: VDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKEL
• Gene Sequence: VDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKEL
• Gene ID - Mouse: ENSMUSG00000061665
• Gene ID - Rat: ENSRNOG00000011987
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti CD2AP pAb (ATL-HPA003326 w/enhanced validation) – 5 Found

Camacho, Jessica; Rábano, Alberto; Marazuela, Paula; Bonaterra-Pastra, Anna; Serna, Garazi; Moliné, Teresa; Ramón Y Cajal, Santiago; Martínez-Sáez, Elena; Hernández-Guillamon, Mar. Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 2022;32(1):e13016. 

Cochran, J Nicholas; Rush, Travis; Buckingham, Susan C; Roberson, Erik D. The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity. Human Molecular Genetics. 2015;24(23):6667-74. 

Haley, Kathryn E; Kronenberg, Nils M; Liehm, Philipp; Elshani, Mustafa; Bell, Cameron; Harrison, David J; Gather, Malte C; Reynolds, Paul A. Podocyte injury elicits loss and recovery of cellular forces. Science Advances. 2018;4(6):eaap8030. 

Furusawa, Kotaro; Takasugi, Toshiyuki; Chiu, Yung-Wen; Hori, Yukiko; Tomita, Taisuke; Fukuda, Mitsunori; Hisanaga, Shin-Ichi. CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway. The Journal Of Biological Chemistry. 2019;294(28):10886-10899. 

Gondaliya, Piyush; P Dasare, Aishwarya; Jash, Kavya; Tekade, Rakesh Kumar; Srivastava, Akshay; Kalia, Kiran. miR-29b attenuates histone deacetylase-4 mediated podocyte dysfunction and renal fibrosis in diabetic nephropathy. Journal Of Diabetes And Metabolic Disorders. 2020;19(1):13-27.