Anti CASP3 mAb (Clone 2B10)

CUSABIO

Catalog No.:
CSB-RA182616A0HU-50
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Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Product Specifications
Application WB, IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 2B10)

Documents & Links for Anti CASP3 mAb (Clone 2B10)
Datasheet Anti CASP3 mAb (Clone 2B10) Datasheet

Documents & Links for Anti CASP3 mAb (Clone 2B10)
Datasheet Anti CASP3 mAb (Clone 2B10) Datasheet