Anti ALDH18A1 pAb (ATL-HPA008333 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA008333-25
  • Immunohistochemical staining of human Colon shows moderate granular cytoplasmic positivity in glandular cells.
  • Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
  • Western blot analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ALDH18A1 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
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Protein Description: aldehyde dehydrogenase 18 family, member A1
Gene Name: ALDH18A1
Alternative Gene Name: GSAS, P5CS, PYCS
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000025007: 99%, ENSRNOG00000060047: 99%
Entrez Gene ID: 5832
Uniprot ID: P54886
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Immunogen SIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKD
Gene Sequence SIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKD
Gene ID - Mouse ENSMUSG00000025007
Gene ID - Rat ENSRNOG00000060047
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.



Documents & Links for Anti ALDH18A1 pAb (ATL-HPA008333 w/enhanced validation)
Datasheet Anti ALDH18A1 pAb (ATL-HPA008333 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ALDH18A1 pAb (ATL-HPA008333 w/enhanced validation)



Citations for Anti ALDH18A1 pAb (ATL-HPA008333 w/enhanced validation) – 3 Found
Stadler, Charlotte; Hjelmare, Martin; Neumann, Beate; Jonasson, Kalle; Pepperkok, Rainer; Uhlén, Mathias; Lundberg, Emma. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. Journal Of Proteomics. 2012;75(7):2236-51.  PubMed
Baqader, Noor O; Radulovic, Marko; Crawford, Mark; Stoeber, Kai; Godovac-Zimmermann, Jasminka. Nuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stress. Journal Of Proteome Research. 2014;13(10):4398-423.  PubMed
Schwörer, Simon; Berisa, Mirela; Violante, Sara; Qin, Weige; Zhu, Jiajun; Hendrickson, Ronald C; Cross, Justin R; Thompson, Craig B. Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress. The Embo Journal. 2020;39(8):e103334.  PubMed