Anti ABCB11 pAb (ATL-HPA019035 w/enhanced validation)

Atlas Antibodies

SKU: ATL-HPA019035-25

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Protein Description: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Gene Name: ABCB11
Alternative Gene Name: ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027048: 79%, ENSRNOG00000050860: 79%
Entrez Gene ID: 8647
Uniprot ID: O95342
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: RLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYFTLVTLQSQGNQALNEEDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILK
• Gene Sequence: RLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYFTLVTLQSQGNQALNEEDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILK
• Gene ID - Mouse: ENSMUSG00000027048
• Gene ID - Rat: ENSRNOG00000050860
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti ABCB11 pAb (ATL-HPA019035 w/enhanced validation) – 4 Found

Vogel, Georg-Friedrich; Maurer, Elisabeth; Entenmann, Andreas; Straub, Simon; Knisely, A S; Janecke, Andreas R; Müller, Thomas. Co-existence of ABCB11 and DCDC2 disease: Infantile cholestasis requires both next-generation sequencing and clinical-histopathologic correlation. European Journal Of Human Genetics : Ejhg. 2020;28(6):840-844. 

Sambrotta, Melissa; Strautnieks, Sandra; Papouli, Efterpi; Rushton, Peter; Clark, Barnaby E; Parry, David A; Logan, Clare V; Newbury, Lucy J; Kamath, Binita M; Ling, Simon; Grammatikopoulos, Tassos; Wagner, Bart E; Magee, John C; Sokol, Ronald J; Mieli-Vergani, Giorgina; Smith, Joshua D; Johnson, Colin A; McClean, Patricia; Simpson, Michael A; Knisely, A S; Bull, Laura N; Thompson, Richard J. Mutations in TJP2 cause progressive cholestatic liver disease. Nature Genetics. 2014;46(4):326-8. 

Blackmore, Laura; Knisely, A S; Hartley, Jane L; McKay, Kirsten; Gissen, Paul; Marcus, Robert; Shawcross, Debbie L. Polymorphisms in ABCB11 and ATP8B1 Associated with Development of Severe Intrahepatic Cholestasis in Hodgkin's Lymphoma. Journal Of Clinical And Experimental Hepatology. 2013;3(2):159-61. 

Okushin, Kazuya; Tsutsumi, Takeya; Ikeuchi, Kazuhiko; Kado, Akira; Enooku, Kenichiro; Fujinaga, Hidetaka; Yamauchi, Naoko; Ushiku, Tetsuo; Moriya, Kyoji; Yotsuyanagi, Hiroshi; Koike, Kazuhiko. Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet. Plos One. 15(8):e0234750.