Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA002199-25
  • Immunohistochemical staining of human kidney shows moderate positivity in apical membrane in cells in distal tubules.
  • Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & focal adhesion sites.
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Protein Description: ATP-binding cassette, sub-family B (MDR/TAP), member 1
Gene Name: ABCB1
Alternative Gene Name: ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000040584: 79%, ENSRNOG00000008012: 76%
Entrez Gene ID: 5243
Uniprot ID: P08183
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen IAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDE
Gene Sequence IAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDE
Gene ID - Mouse ENSMUSG00000040584
Gene ID - Rat ENSRNOG00000008012
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation)
Datasheet Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation)
Datasheet Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation)



Citations for Anti ABCB1 pAb (ATL-HPA002199 w/enhanced validation) – 4 Found
Bernstein, Hans-Gert; Hölzl, Gloria; Dobrowolny, Henrik; Hildebrandt, Jens; Trübner, Kurt; Krohn, Markus; Bogerts, Bernhard; Pahnke, Jens. Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. Mechanisms Of Ageing And Development. 2014;141-142( 25218792):12-21.  PubMed
Xie, Yuan; He, Liqun; Lugano, Roberta; Zhang, Yanyu; Cao, Haiyan; He, Qiyuan; Chao, Min; Liu, Boxuan; Cao, Qingze; Wang, Jianhao; Jiao, Yang; Hu, Yaqin; Han, Liying; Zhang, Yong; Huang, Hua; Uhrbom, Lene; Betsholtz, Christer; Wang, Liang; Dimberg, Anna; Zhang, Lei. Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing. Jci Insight. 2021;6(15)  PubMed
Trumpi, K; Emmink, B L; Prins, A M; van Oijen, M G H; van Diest, P J; Punt, C J A; Koopman, M; Kranenburg, O; Rinkes, I H M Borel. ABC-Transporter Expression Does Not Correlate with Response to Irinotecan in Patients with Metastatic Colorectal Cancer. Journal Of Cancer. 6(11):1079-86.  PubMed
Berg, Tove; Hegelund-Myrbäck, Tove; Öckinger, Johan; Zhou, Xiao-Hong; Brännström, Marie; Hagemann-Jensen, Michael; Werkström, Viktoria; Seidegård, Janeric; Grunewald, Johan; Nord, Magnus; Gustavsson, Lena. Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals. Respiratory Research. 2018;19(1):68.  PubMed