According to the MISEV2018 guidelines established by the International Society for Extracellular Vesicles (ISEV), a comprehensive EV characterization strategy should include the detection of multiple classes of markers: transmembrane or membrane-associated proteins, cytosolic proteins with membrane-binding properties, and confirmation of the absence of negative markers that indicate contamination from intracellular organelles.
Cosmo Bio USA offers an extensive portfolio of Antibodies, Proteins, Peptides, and ELISA kits for detecting a variety of EV markers via western blotting, flow cytometry, ELISA and mass spectrometry. Browse our solutions for EV characterization below.