UVC-Irradiated DNA Samples

Cosmo Bio

Catalog No.: CSR-NM-MA-R010

"UVC-Irradiated DNA Samples" were made by irradiating calf thymus DNA with various doses of UVC (mainly 254 nm) including 0, 2.5, 5, 7.5 and 10 J/m2 . Two major DNA damage, cyclobutane pyrimidine dimers (CPD) and (6-4) photoproducts (6-4PP), are formed in UV-irradiated DNA. These DNA samples are useful to make a standard dose-response curve in ELISA or other immunological assays.

Citations for UVC-Irradiated DNA Samples – 3 Found

Hird, Coen; Franklin, Craig E; Cramp, Rebecca L. Temperature causes species-specific responses to UV-induced DNA damage in amphibian larvae. Biology Letters. 2022;18(10):20220358. 

Steurer, Barbara; Turkyilmaz, Yasemin; van Toorn, Marvin; van Leeuwen, Wessel; Escudero-Ferruz, Paula; Marteijn, Jurgen A. Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair. Nucleic Acids Research. 2019;47(7):3536-3549. 

Murata, Yasumasa; Osakabe, Masahiro. Photo-enzymatic repair of UVB-induced DNA damage in the two-spotted spider mite Tetranychus urticae. Experimental & Applied Acarology. 2017;71(1):15-34.