Anti SUN2 pAb (ATL-HPA001209 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA001209-25

Protein Description: Sad1 and UNC84 domain containing 2
Gene Name: SUN2
Alternative Gene Name: UNC84B
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000042524: 78%, ENSRNOG00000015177: 80%
Entrez Gene ID: 25777
Uniprot ID: Q9UH99
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSE
• Gene Sequence: LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSE
• Gene ID - Mouse: ENSMUSG00000042524
• Gene ID - Rat: ENSRNOG00000015177
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti SUN2 pAb (ATL-HPA001209 w/enhanced validation) – 12 Found

Lv, Xiao-bin; Liu, Lijuan; Cheng, Chun; Yu, Bentong; Xiong, Longxin; Hu, Kaishun; Tang, Jianjun; Zeng, Lei; Sang, Yi. SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer. Scientific Reports. 2015;5( 26658802):17940. 

Yin, Yan; Zhong, Jun; Li, Si-Wei; Li, Jian-Zhe; Zhou, Min; Chen, Yin; Sang, Yi; Liu, Lijuan. TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer. Oncotarget. 2016;7(52):86755-86765. 

Bonnin, Edith; Cabochette, Pauline; Filosa, Alessandro; Jühlen, Ramona; Komatsuzaki, Shoko; Hezwani, Mohammed; Dickmanns, Achim; Martinelli, Valérie; Vermeersch, Marjorie; Supply, Lynn; Martins, Nuno; Pirenne, Laurence; Ravenscroft, Gianina; Lombard, Marcus; Port, Sarah; Spillner, Christiane; Janssens, Sandra; Roets, Ellen; Van Dorpe, Jo; Lammens, Martin; Kehlenbach, Ralph H; Ficner, Ralf; Laing, Nigel G; Hoffmann, Katrin; Vanhollebeke, Benoit; Fahrenkrog, Birthe. Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence. Plos Genetics. 2018;14(12):e1007845. 

Chiarini, Francesca; Paganelli, Francesca; Balestra, Tommaso; Capanni, Cristina; Fazio, Antonietta; Manara, Maria Cristina; Landuzzi, Lorena; Petrini, Stefania; Evangelisti, Camilla; Lollini, Pier-Luigi; Martelli, Alberto M; Lattanzi, Giovanna; Scotlandi, Katia. Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma. Cell Death & Disease. 2022;13(4):346. 

Gudise, Santhosh; Figueroa, Ricardo A; Lindberg, Robert; Larsson, Veronica; Hallberg, Einar. Samp1 is functionally associated with the LINC complex and A-type lamina networks. Journal Of Cell Science. 2011;124(Pt 12):2077-85. 

Stadler, Charlotte; Rexhepaj, Elton; Singan, Vasanth R; Murphy, Robert F; Pepperkok, Rainer; Uhlén, Mathias; Simpson, Jeremy C; Lundberg, Emma. Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nature Methods. 2013;10(4):315-23. 

Horn, Henning F; Kim, Dae In; Wright, Graham D; Wong, Esther Sook Miin; Stewart, Colin L; Burke, Brian; Roux, Kyle J. A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. The Journal Of Cell Biology. 2013;202(7):1023-39. 

Alsarraj, Jude; Faraji, Farhoud; Geiger, Thomas R; Mattaini, Katherine R; Williams, Mia; Wu, Josephine; Ha, Ngoc-Han; Merlino, Tyler; Walker, Renard C; Bosley, Allen D; Xiao, Zhen; Andresson, Thorkell; Esposito, Dominic; Smithers, Nicholas; Lugo, Dave; Prinjha, Rab; Day, Anup; Crawford, Nigel P S; Ozato, Keiko; Gardner, Kevin; Hunter, Kent W. BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane. Plos One. 8(11):e80746. 

Chaumet, Alexandre; Wright, Graham D; Seet, Sze Hwee; Tham, Keit Min; Gounko, Natalia V; Bard, Frederic. Nuclear envelope-associated endosomes deliver surface proteins to the nucleus. Nature Communications. 2015;6( 26356418):8218. 

Fahrenkrog, Birthe; Martinelli, Valérie; Nilles, Nadine; Fruhmann, Gernot; Chatel, Guillaume; Juge, Sabine; Sauder, Ursula; Di Giacomo, Danika; Mecucci, Cristina; Schwaller, Jürg. Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype. Plos One. 11(3):e0152321. 

Gilbert, Hamish T J; Mallikarjun, Venkatesh; Dobre, Oana; Jackson, Mark R; Pedley, Robert; Gilmore, Andrew P; Richardson, Stephen M; Swift, Joe. Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading. Nature Communications. 2019;10(1):4149. 

Svobodová Kovaříková, Alena; Bártová, Eva; Kovařík, Aleš; Lukášová, Emilie. Spatiotemporal Mislocalization of Nuclear Membrane-Associated Proteins in γ-Irradiation-Induced Senescent Cells. Cells. 2020;9(4)