Anti SON pAb (ATL-HPA023535)

Atlas Antibodies

Catalog No.: ATL-HPA023535-25

Protein Description: SON DNA binding protein
Gene Name: SON
Alternative Gene Name: BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000022961: 59%, ENSRNOG00000002021: 60%
Entrez Gene ID: 6651
Uniprot ID: P18583
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: TEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGP
• Gene Sequence: TEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGP
• Gene ID - Mouse: ENSMUSG00000022961
• Gene ID - Rat: ENSRNOG00000002021
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti SON pAb (ATL-HPA023535) – 12 Found

Shorbagi, Sadek; Brown, Ian R. Dynamics of the association of heat shock protein HSPA6 (Hsp70B') and HSPA1A (Hsp70-1) with stress-sensitive cytoplasmic and nuclear structures in differentiated human neuronal cells. Cell Stress & Chaperones. 2016;21(6):993-1003. 

Deane, Catherine A S; Brown, Ian R. Components of a mammalian protein disaggregation/refolding machine are targeted to nuclear speckles following thermal stress in differentiated human neuronal cells. Cell Stress & Chaperones. 2017;22(2):191-200. 

Deane, Catherine A S; Brown, Ian R. Differential Targeting of Hsp70 Heat Shock Proteins HSPA6 and HSPA1A with Components of a Protein Disaggregation/Refolding Machine in Differentiated Human Neuronal Cells following Thermal Stress. Frontiers In Neuroscience. 11( 28484369):227. 

Chen, Yu; Zhang, Yang; Wang, Yuchuan; Zhang, Liguo; Brinkman, Eva K; Adam, Stephen A; Goldman, Robert; van Steensel, Bas; Ma, Jian; Belmont, Andrew S. Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler. The Journal Of Cell Biology. 2018;217(11):4025-4048. 

Fuchs, Florian; Pau, Gregoire; Kranz, Dominique; Sklyar, Oleg; Budjan, Christoph; Steinbrink, Sandra; Horn, Thomas; Pedal, Angelika; Huber, Wolfgang; Boutros, Michael. Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Molecular Systems Biology. 2010;6( 20531400):370. 

Uhlén, Mathias; Oksvold, Per; Älgenäs, Cajsa; Hamsten, Carl; Fagerberg, Linn; Klevebring, Daniel; Lundberg, Emma; Odeberg, Jacob; Pontén, Fredrik; Kondo, Tadashi; Sivertsson, Åsa. Antibody-based protein profiling of the human chromosome 21. Molecular & Cellular Proteomics : Mcp. 2012;11(3):M111.013458. 

Ammon, Tim; Mishra, Shravan Kumar; Kowalska, Kaja; Popowicz, Grzegorz M; Holak, Tad A; Jentsch, Stefan. The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. Journal Of Molecular Cell Biology. 2014;6(4):312-23. 

Kuga, Takahisa; Kume, Hideaki; Adachi, Jun; Kawasaki, Naoko; Shimizu, Maiko; Hoshino, Isamu; Matsubara, Hisahiro; Saito, Youhei; Nakayama, Yuji; Tomonaga, Takeshi. Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON. Scientific Reports. 2016;6( 27681590):34472. 

Kim, Jiah; Han, Kyu Young; Khanna, Nimish; Ha, Taekjip; Belmont, Andrew S. Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition. Journal Of Cell Science. 2019;132(8) 

Ilik, İbrahim Avşar; Malszycki, Michal; Lübke, Anna Katharina; Schade, Claudia; Meierhofer, David; Aktaş, Tuğçe. SON and SRRM2 are essential for nuclear speckle formation. Elife. 2020;9( 33095160) 

Yildirim, Adem; Mozaffari-Jovin, Sina; Wallisch, Ann-Kathrin; Schäfer, Jessica; Ludwig, Sebastian E J; Urlaub, Henning; Lührmann, Reinhard; Wolfrum, Uwe. SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes. Nucleic Acids Research. 2021;49(10):5845-5866. 

Kumar, Anurendra; Schrader, Alex W; Boroojeny, Ali Ebrahimpour; Asadian, Marisa; Lee, Juyeon; Song, You Jin; Zhao, Sihai Dave; Han, Hee-Sun; Sinha, Saurabh. Intracellular Spatial Transcriptomic Analysis Toolkit (InSTAnT). Research Square. 2023; 36747718( 36747718)