Anti OGDH pAb (ATL-HPA020347)

Atlas Antibodies

Catalog No.: ATL-HPA020347-25

Protein Description: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Gene Name: OGDH
Alternative Gene Name: E1k
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000020456: 94%, ENSRNOG00000005130: 94%
Entrez Gene ID: 4967
Uniprot ID: Q02218
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: FRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQ
• Gene Sequence: FRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQ
• Gene ID - Mouse: ENSMUSG00000020456
• Gene ID - Rat: ENSRNOG00000005130
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti OGDH pAb (ATL-HPA020347) – 5 Found

Ilic, Nina; Birsoy, Kıvanç; Aguirre, Andrew J; Kory, Nora; Pacold, Michael E; Singh, Shambhavi; Moody, Susan E; DeAngelo, Joseph D; Spardy, Nicole A; Freinkman, Elizaveta; Weir, Barbara A; Tsherniak, Aviad; Cowley, Glenn S; Root, David E; Asara, John M; Vazquez, Francisca; Widlund, Hans R; Sabatini, David M; Hahn, William C. PIK3CA mutant tumors depend on oxoglutarate dehydrogenase. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2017;114(17):E3434-E3443. 

Ast, Tslil; Meisel, Joshua D; Patra, Shachin; Wang, Hong; Grange, Robert M H; Kim, Sharon H; Calvo, Sarah E; Orefice, Lauren L; Nagashima, Fumiaki; Ichinose, Fumito; Zapol, Warren M; Ruvkun, Gary; Barondeau, David P; Mootha, Vamsi K. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019;177(6):1507-1521.e16. 

Dobolyi, Arpad; Bago, Attila; Palkovits, Miklos; Nemeria, Natalia S; Jordan, Frank; Doczi, Judit; Ambrus, Attila; Adam-Vizi, Vera; Chinopoulos, Christos. Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation. Brain Structure & Function. 2020;225(2):639-667. 

Kafkia, Eleni; Andres-Pons, Amparo; Ganter, Kerstin; Seiler, Markus; Smith, Tom S; Andrejeva, Anna; Jouhten, Paula; Pereira, Filipa; Franco, Catarina; Kuroshchenkova, Anna; Leone, Sergio; Sawarkar, Ritwick; Boston, Rebecca; Thaventhiran, James; Zaugg, Judith B; Lilley, Kathryn S; Lancrin, Christophe; Beck, Martin; Patil, Kiran Raosaheb. Operation of a TCA cycle subnetwork in the mammalian nucleus. Science Advances. 2022;8(35):eabq5206. 

Forny, Patrick; Bonilla, Ximena; Lamparter, David; Shao, Wenguang; Plessl, Tanja; Frei, Caroline; Bingisser, Anna; Goetze, Sandra; van Drogen, Audrey; Harshman, Keith; Pedrioli, Patrick G A; Howald, Cedric; Poms, Martin; Traversi, Florian; Bürer, Céline; Cherkaoui, Sarah; Morscher, Raphael J; Simmons, Luke; Forny, Merima; Xenarios, Ioannis; Aebersold, Ruedi; Zamboni, Nicola; Rätsch, Gunnar; Dermitzakis, Emmanouil T; Wollscheid, Bernd; Baumgartner, Matthias R; Froese, D Sean. Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature Metabolism. 2023;5(1):80-95.