Anti LRBA pAb (ATL-HPA023597)

Atlas Antibodies

Catalog No.: ATL-HPA023597-25

Protein Description: LPS-responsive vesicle trafficking, beach and anchor containing
Gene Name: LRBA
Alternative Gene Name: BGL, CDC4L, LAB300, LBA
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000028080: 67%, ENSRNOG00000023453: 65%
Entrez Gene ID: 987
Uniprot ID: P50851
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: GGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGNENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETL
• Gene Sequence: GGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGNENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETL
• Gene ID - Mouse: ENSMUSG00000028080
• Gene ID - Rat: ENSRNOG00000023453
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti LRBA pAb (ATL-HPA023597) – 11 Found

Massaad, Michel J; Zhou, Jia; Tsuchimoto, Daisuke; Chou, Janet; Jabara, Haifa; Janssen, Erin; Glauzy, Salomé; Olson, Brennan G; Morbach, Henner; Ohsumi, Toshiro K; Schmitz, Klaus; Kyriacos, Markianos; Kane, Jennifer; Torisu, Kumiko; Nakabeppu, Yusaku; Notarangelo, Luigi D; Chouery, Eliane; Megarbane, Andre; Kang, Peter B; Al-Idrissi, Eman; Aldhekri, Hasan; Meffre, Eric; Mizui, Masayuki; Tsokos, George C; Manis, John P; Al-Herz, Waleed; Wallace, Susan S; Geha, Raif S. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. The Journal Of Clinical Investigation. 2016;126(11):4219-4236. 

Bakhtiar, Shahrzad; Gámez-Díaz, Laura; Jarisch, Andrea; Soerensen, Jan; Grimbacher, Bodo; Belohradsky, Bernd; Keller, Klaus-Michael; Rietschel, Christoph; Klingebiel, Thomas; Koletzko, Sibylle; Albert, Michael H; Bader, Peter. Treatment of Infantile Inflammatory Bowel Disease and Autoimmunity by Allogeneic Stem Cell Transplantation in LPS-Responsive Beige-Like Anchor Deficiency. Frontiers In Immunology. 8( 28197149):52. 

Charbit-Henrion, Fabienne; Parlato, Marianna; Hanein, Sylvain; Duclaux-Loras, Rémi; Nowak, Jan; Begue, Bernadette; Rakotobe, Sabine; Bruneau, Julie; Fourrage, Cécile; Alibeu, Olivier; Rieux-Laucat, Frédéric; Lévy, Eva; Stolzenberg, Marie-Claude; Mazerolles, Fabienne; Latour, Sylvain; Lenoir, Christelle; Fischer, Alain; Picard, Capucine; Aloi, Marina; Dias, Jorge Amil; Hariz, Mongi Ben; Bourrier, Anne; Breuer, Christian; Breton, Anne; Bronsky, Jiri; Buderus, Stephan; Cananzi, Mara; Coopman, Stéphanie; Crémilleux, Clara; Dabadie, Alain; Dumant-Forest, Clémentine; Gurkan, Odul Egritas; Fabre, Alexandre; Fischer, Aude; Diaz, Marta German; Gonzalez-Lama, Yago; Goulet, Olivier; Guariso, Graziella; Gurcan, Neslihan; Homan, Matjaz; Hugot, Jean-Pierre; Jeziorski, Eric; Karanika, Evi; Lachaux, Alain; Lewindon, Peter; Lima, Rosa; Magro, Fernando; Major, Janos; Malamut, Georgia; Mas, Emmanuel; Mattyus, Istvan; Mearin, Luisa M; Melek, Jan; Navas-Lopez, Victor Manuel; Paerregaard, Anders; Pelatan, Cecile; Pigneur, Bénédicte; Pais, Isabel Pinto; Rebeuh, Julie; Romano, Claudio; Siala, Nadia; Strisciuglio, Caterina; Tempia-Caliera, Michela; Tounian, Patrick; Turner, Dan; Urbonas, Vaidotas; Willot, Stéphanie; Ruemmele, Frank M; Cerf-Bensussan, Nadine. Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre Study. Journal Of Crohn's & Colitis. 2018;12(9):1104-1112. 

Lopez-Herrera, Gabriela; Tampella, Giacomo; Pan-Hammarström, Qiang; Herholz, Peer; Trujillo-Vargas, Claudia M; Phadwal, Kanchan; Simon, Anna Katharina; Moutschen, Michel; Etzioni, Amos; Mory, Adi; Srugo, Izhak; Melamed, Doron; Hultenby, Kjell; Liu, Chonghai; Baronio, Manuela; Vitali, Massimiliano; Philippet, Pierre; Dideberg, Vinciane; Aghamohammadi, Asghar; Rezaei, Nima; Enright, Victoria; Du, Likun; Salzer, Ulrich; Eibel, Hermann; Pfeifer, Dietmar; Veelken, Hendrik; Stauss, Hans; Lougaris, Vassilios; Plebani, Alessandro; Gertz, E Michael; Schäffer, Alejandro A; Hammarström, Lennart; Grimbacher, Bodo. Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity. American Journal Of Human Genetics. 2012;90(6):986-1001. 

Bakhtiar, Shahrzad; Ruemmele, Frank; Charbit-Henrion, Fabienne; Lévy, Eva; Rieux-Laucat, Frédéric; Cerf-Bensussan, Nadine; Bader, Peter; Paetow, Ulrich. Atypical Manifestation of LPS-Responsive Beige-Like Anchor Deficiency Syndrome as an Autoimmune Endocrine Disorder without Enteropathy and Immunodeficiency. Frontiers In Pediatrics. 4( 27683652):98. 

Kostel Bal, Sevgi; Haskologlu, Sule; Serwas, Nina K; Islamoglu, Candan; Aytekin, Caner; Kendirli, Tanil; Kuloglu, Zarife; Yavuz, Gulsan; Dalgic, Buket; Siklar, Zeynep; Kansu, Aydan; Ensari, Arzu; Boztug, Kaan; Dogu, Figen; Ikinciogullari, Aydan. Multiple Presentations of LRBA Deficiency: a Single-Center Experience. Journal Of Clinical Immunology. 2017;37(8):790-800. 

Gámez-Díaz, Laura; Sigmund, Elena C; Reiser, Veronika; Vach, Werner; Jung, Sophie; Grimbacher, Bodo. Rapid Flow Cytometry-Based Test for the Diagnosis of Lipopolysaccharide Responsive Beige-Like Anchor (LRBA) Deficiency. Frontiers In Immunology. 9( 29740429):720. 

Zhang, Yan; Du, Xuexiang; Liu, Mingyue; Tang, Fei; Zhang, Peng; Ai, Chunxia; Fields, James K; Sundberg, Eric J; Latinovic, Olga S; Devenport, Martin; Zheng, Pan; Liu, Yang. Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy. Cell Research. 2019;29(8):609-627. 

Martínez-Jaramillo, Catalina; Gutierrez-Hincapie, Sebastian; Arango, Julio César Orrego; Vásquez-Duque, Gloria María; Erazo-Garnica, Ruth María; Franco, Jose Luis; Trujillo-Vargas, Claudia Milena. Clinical, immunological and genetic characteristic of patients with clinical phenotype associated to LRBA-deficiency in Colombia. Colombia Medica (Cali, Colombia). 2019;50(3):176-191. 

Totsune, Eriko; Nakano, Tomohiro; Moriya, Kunihiko; Sato, Daichi; Suzuki, Dai; Miura, Akinobu; Katayama, Saori; Niizuma, Hidetaka; Kanno, Junko; van Zelm, Menno C; Imai, Kohsuke; Kanegane, Hirokazu; Sasahara, Yoji; Kure, Shigeo. Case Report: Infantile-Onset Fulminant Type 1 Diabetes Mellitus Caused by Novel Compound Heterozygous LRBA Variants. Frontiers In Immunology. 12( 33912197):677572. 

Tang, Wen-Juan; Hu, Wen-Hui; Huang, Ying; Wu, Bing-Bing; Peng, Xiao-Min; Zhai, Xiao-Wen; Qian, Xiao-Wen; Ye, Zi-Qing; Xia, Hai-Jiao; Wu, Jie; Shi, Jie-Ru. Potential protein-phenotype correlation in three lipopolysaccharide-responsive beige-like anchor protein-deficient patients. World Journal Of Clinical Cases. 2021;9(21):5873-5888.