Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA004712-25
  • Immunohistochemistry analysis in human duodenum and tonsil tissues using HPA004712 antibody. Corresponding HNF4A RNA-seq data are presented for the same tissues.
  • Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.
  • Western blot analysis in human cell lines Caco-2 and PC-3 using Anti-HNF4A antibody. Corresponding HNF4A RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.
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Protein Description: hepatocyte nuclear factor 4, alpha
Gene Name: HNF4A
Alternative Gene Name: HNF4, MODY, MODY1, NR2A1, TCF14
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000017950: 91%, ENSRNOG00000008895: 92%
Entrez Gene ID: 3172
Uniprot ID: P41235
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC, ChIP-Exo-Seq
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEV
Gene Sequence LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEV
Gene ID - Mouse ENSMUSG00000017950
Gene ID - Rat ENSRNOG00000008895
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation)
Datasheet Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation)
Datasheet Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation)



Citations for Anti HNF4A pAb (ATL-HPA004712 w/enhanced validation) – 5 Found
Mezentsev, Alexandre; Amundson, Sally A. Global gene expression responses to low- or high-dose radiation in a human three-dimensional tissue model. Radiation Research. 2011;175(6):677-88.  PubMed
Wang, Zhu; Li, Youjia; Wu, Dinglan; Yu, Shan; Wang, Yuliang; Leung Chan, Franky. Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence. Oncogene. 2020;39(7):1572-1589.  PubMed
Labour, Marie-Noëlle; Le Guilcher, Camile; Aid-Launais, Rachida; El Samad, Nour; Lanouar, Soraya; Simon-Yarza, Teresa; Letourneur, Didier. Development of 3D Hepatic Constructs Within Polysaccharide-Based Scaffolds with Tunable Properties. International Journal Of Molecular Sciences. 2020;21(10)  PubMed
Guldiken, Nurdan; Argemi, Josepmaria; Gurbuz, Berivan; Atkinson, Stephen R; Oliverius, Martin; Fila, Petr; Hamesch, Karim; Bruns, Tony; Cabezas, Joaquín; Lozano, Juan J; Mann, Jelena; Cao, Sheng; Mathurin, Philippe; Shah, Vijay H; Trautwein, Christian; Thursz, Mark R; Bataller, Ramon; Strnad, Pavel. Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases. Bmc Medicine. 2021;19(1):39.  PubMed
Li, Rong; Zhao, Yang; Yourick, Jeffrey J; Sprando, Robert L; Gao, Xiugong. Phenotypical, functional and transcriptomic comparison of two modified methods of hepatocyte differentiation from human induced pluripotent stem cells. Biomedical Reports. 2022;16(5):43.  PubMed