Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA042979-25
  • Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.
  • Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
  • Western blot analysis in human cell lines PC-3 and HeLa using Anti-ECSIT antibody. Corresponding ECSIT RNA-seq data are presented for the same cell lines. Loading control: Anti-HSP90B1.
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Protein Description: ECSIT signalling integrator
Gene Name: ECSIT
Alternative Gene Name: SITPEC
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000066839: 84%, ENSRNOG00000014128: 85%
Entrez Gene ID: 51295
Uniprot ID: Q9BQ95
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Immunogen HMEPDLSARVTIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPM
Gene Sequence HMEPDLSARVTIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPM
Gene ID - Mouse ENSMUSG00000066839
Gene ID - Rat ENSRNOG00000014128
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation)
Datasheet Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation)
Datasheet Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation)



Citations for Anti ECSIT pAb (ATL-HPA042979 w/enhanced validation) – 1 Found
Lin, Chujiao; Yang, Qiyuan; Guo, Dongsheng; Xie, Jun; Yang, Yeon-Suk; Chaugule, Sachin; DeSouza, Ngoc; Oh, Won-Taek; Li, Rui; Chen, Zhihao; John, Aijaz A; Qiu, Qiang; Zhu, Lihua Julie; Greenblatt, Matthew B; Ghosh, Sankar; Li, Shaoguang; Gao, Guangping; Haynes, Cole; Emerson, Charles P; Shim, Jae-Hyuck. Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nature Communications. 2022;13(1):6869.  PubMed