Anti SEPT2 pAb (ATL-HPA018481 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA018481-25

Protein Description: septin 2
Gene Name: SEPT2
Alternative Gene Name: DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000112508: 97%, ENSRNOG00000017952: 96%
Entrez Gene ID: 4735
Uniprot ID: Q15019
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: WGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDGDGGALGH
• Gene Sequence: WGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDGDGGALGH
• Gene ID - Mouse: ENSMUSG00000112508
• Gene ID - Rat: ENSRNOG00000017952
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti SEPT2 pAb (ATL-HPA018481 w/enhanced validation) – 9 Found

Lu, Hao; Galeano, Maria C Rondón; Ott, Elisabeth; Kaeslin, Geraldine; Kausalya, P Jaya; Kramer, Carina; Ortiz-Brüchle, Nadina; Hilger, Nadescha; Metzis, Vicki; Hiersche, Milan; Tay, Shang Yew; Tunningley, Robert; Vij, Shubha; Courtney, Andrew D; Whittle, Belinda; Wühl, Elke; Vester, Udo; Hartleben, Björn; Neuber, Steffen; Frank, Valeska; Little, Melissa H; Epting, Daniel; Papathanasiou, Peter; Perkins, Andrew C; Wright, Graham D; Hunziker, Walter; Gee, Heon Yung; Otto, Edgar A; Zerres, Klaus; Hildebrandt, Friedhelm; Roy, Sudipto; Wicking, Carol; Bergmann, Carsten. Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease. Nature Genetics. 2017;49(7):1025-1034. 

Song, Kyungyeun; Gras, Claudia; Capin, Gabrielle; Gimber, Niclas; Lehmann, Martin; Mohd, Saif; Puchkov, Dmytro; Rödiger, Maria; Wilhelmi, Ilka; Daumke, Oliver; Schmoranzer, Jan; Schürmann, Annette; Krauss, Michael. A SEPT1-based scaffold is required for Golgi integrity and function. Journal Of Cell Science. 2019;132(3) 

Banko, Monika; Mucha-Kruczynska, Iwona; Weise, Christoph; Heyd, Florian; Ewers, Helge. A homozygous genome-edited Sept2-EGFP fibroblast cell line. Cytoskeleton (Hoboken, N.j.). 2019;76(1):73-82. 

Kim, Joanna; Cooper, John A. Junctional Localization of Septin 2 Is Required for Organization of Junctional Proteins in Static Endothelial Monolayers. Arteriosclerosis, Thrombosis, And Vascular Biology. 2021;41(1):346-359. 

Froidevaux-Klipfel, Laurence; Poirier, Florence; Boursier, Céline; Crépin, Ronan; Poüs, Christian; Baudin, Bruno; Baillet, Anita. Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol-resistant human breast cancer cell line MDA-MB-231. Proteomics. 2011;11(19):3877-86. 

Volceanov, Larisa; Herbst, Katharina; Biniossek, Martin; Schilling, Oliver; Haller, Dirk; Nölke, Thilo; Subbarayal, Prema; Rudel, Thomas; Zieger, Barbara; Häcker, Georg. Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion. Mbio. 2014;5(5):e01802-14. 

Dille, Stephanie; Kleinschnitz, Eva-Maria; Kontchou, Collins Waguia; Nölke, Thilo; Häcker, Georg. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infection And Immunity. 2015;83(8):3268-80. 

Collins, Kerrie B; Kang, Hojin; Matsche, Jacob; Klomp, Jennifer E; Rehman, Jalees; Malik, Asrar B; Karginov, Andrei V. Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis. The Journal Of Cell Biology. 2020;219(2) 

Park, Hyun-Sook; Papanastasi, Eirini; Blanchard, Gabriela; Chiticariu, Elena; Bachmann, Daniel; Plomann, Markus; Morice-Picard, Fanny; Vabres, Pierre; Smahi, Asma; Huber, Marcel; Pich, Christine; Hohl, Daniel. ARP-T1-associated Bazex-Dupré-Christol syndrome is an inherited basal cell cancer with ciliary defects characteristic of ciliopathies. Communications Biology. 2021;4(1):544.