Anti MYO1C pAb (ATL-HPA001768 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA001768-25

Protein Description: myosin IC
Gene Name: MYO1C
Alternative Gene Name: myr2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000017774: 96%, ENSRNOG00000004072: 96%
Entrez Gene ID: 4641
Uniprot ID: O00159
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: GEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLV
• Gene Sequence: GEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLV
• Gene ID - Mouse: ENSMUSG00000017774
• Gene ID - Rat: ENSRNOG00000004072
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti MYO1C pAb (ATL-HPA001768 w/enhanced validation) – 7 Found

Brandstaetter, Hemma; Kishi-Itakura, Chieko; Tumbarello, David A; Manstein, Dietmar J; Buss, Folma. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 10(12):2310-23. 

Nevzorov, Ilja; Sidorenko, Ekaterina; Wang, Weihuan; Zhao, Hongxia; Vartiainen, Maria K. Myosin-1C uses a novel phosphoinositide-dependent pathway for nuclear localization. Embo Reports. 2018;19(2):290-304. 

Tiwari, Ajit; Jung, Jae-Joon; Inamdar, Shivangi M; Nihalani, Deepak; Choudhury, Amit. The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling. American Journal Of Physiology. Heart And Circulatory Physiology. 2013;304(5):H687-96. 

Hedberg Oldfors, Carola; Dios, Diego Garcia; Linder, Anna; Visuttijai, Kittichate; Samuelson, Emma; Karlsson, Sandra; Nilsson, Staffan; Behboudi, Afrouz. Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region. Bmc Genetics. 2015;16( 26170120):80. 

Visuttijai, Kittichate; Pettersson, Jennifer; Mehrbani Azar, Yashar; van den Bout, Iman; Örndal, Charlotte; Marcickiewicz, Janusz; Nilsson, Staffan; Hörnquist, Michael; Olsson, Björn; Ejeskär, Katarina; Behboudi, Afrouz. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. Plos One. 11(10):e0164063. 

Lehtimäki, Jaakko I; Fenix, Aidan M; Kotila, Tommi M; Balistreri, Giuseppe; Paavolainen, Lassi; Varjosalo, Markku; Burnette, Dylan T; Lappalainen, Pekka. UNC-45a promotes myosin folding and stress fiber assembly. The Journal Of Cell Biology. 2017;216(12):4053-4072. 

Di Pisa, Filippo; Pesenti, Elisa; Bono, Maria; Mazzarello, Andrea N; Bernardi, Cinzia; Lisanti, Michael P; Renzone, Giovanni; Scaloni, Andrea; Ciccone, Ermanno; Fais, Franco; Bruno, Silvia; Scartezzini, Paolo; Ghiotto, Fabio. SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line. Bmc Molecular And Cell Biology. 2021;22(1):41.