Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA011868-25
  • Immunohistochemical staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.
  • Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
  • Western blot analysis in control (vector only transfected HEK293T lysate) and DKK3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY415712).
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Protein Description: dickkopf WNT signaling pathway inhibitor 3
Gene Name: DKK3
Alternative Gene Name: REIC, RIG
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000030772: 83%, ENSRNOG00000016343: 81%
Entrez Gene ID: 27122
Uniprot ID: Q9UBP4
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen CGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYLAASW
Gene Sequence CGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYLAASW
Gene ID - Mouse ENSMUSG00000030772
Gene ID - Rat ENSRNOG00000016343
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation)
Datasheet Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation)
Datasheet Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation)



Citations for Anti DKK3 pAb (ATL-HPA011868 w/enhanced validation) – 2 Found
Ferrari, Nicola; Ranftl, Romana; Chicherova, Ievgeniia; Slaven, Neil D; Moeendarbary, Emad; Farrugia, Aaron J; Lam, Maxine; Semiannikova, Maria; Westergaard, Marie C W; Tchou, Julia; Magnani, Luca; Calvo, Fernando. Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts. Nature Communications. 2019;10(1):130.  PubMed
Rivellese, Felice; Surace, Anna E A; Goldmann, Katriona; Sciacca, Elisabetta; Çubuk, Cankut; Giorli, Giovanni; John, Christopher R; Nerviani, Alessandra; Fossati-Jimack, Liliane; Thorborn, Georgina; Ahmed, Manzoor; Prediletto, Edoardo; Church, Sarah E; Hudson, Briana M; Warren, Sarah E; McKeigue, Paul M; Humby, Frances; Bombardieri, Michele; Barnes, Michael R; Lewis, Myles J; Pitzalis, Costantino. Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Nature Medicine. 2022;28(6):1256-1268.  PubMed