Anti CDK1 pAb (ATL-HPA003387 w/enhanced validation)

Atlas Antibodies

SKU: ATL-HPA003387-25

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Protein Description: cyclin-dependent kinase 1
Gene Name: CDK1
Alternative Gene Name: CDC2, CDC28A
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000019942: 98%, ENSRNOG00000000632: 98%
Entrez Gene ID: 983
Uniprot ID: P06493
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: LGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
• Gene Sequence: LGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
• Gene ID - Mouse: ENSMUSG00000019942
• Gene ID - Rat: ENSRNOG00000000632
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti CDK1 pAb (ATL-HPA003387 w/enhanced validation) – 10 Found

Xu, Guilian; Pattamatta, Amrutha; Hildago, Ryan; Pace, Michael C; Brown, Hilda; Borchelt, David R. Vulnerability of newly synthesized proteins to proteostasis stress. Journal Of Cell Science. 2016;129(9):1892-901. 

Goto, Yusuke; Kurozumi, Akira; Arai, Takayuki; Nohata, Nijiro; Kojima, Satoko; Okato, Atsushi; Kato, Mayuko; Yamazaki, Kazuto; Ishida, Yasuo; Naya, Yukio; Ichikawa, Tomohiko; Seki, Naohiko. Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer. British Journal Of Cancer. 2017;117(3):409-420. 

Marlier, Quentin; Jibassia, Florian; Verteneuil, Sébastien; Linden, Jérôme; Kaldis, Philipp; Meijer, Laurent; Nguyen, Laurent; Vandenbosch, Renaud; Malgrange, Brigitte. Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death. Cell Death Discovery. 4( 29581894):43. 

Sousa, Mirta M L; Zub, Kamila Anna; Aas, Per Arne; Hanssen-Bauer, Audun; Demirovic, Aida; Sarno, Antonio; Tian, Erming; Liabakk, Nina B; Slupphaug, Geir. An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells. Plos One. 8(2):e55493. 

Lukinavičius, Gražvydas; Lavogina, Darja; Gönczy, Pierre; Johnsson, Kai. Commercial Cdk1 antibodies recognize the centrosomal protein Cep152. Biotechniques. 2013;55(3):111-4. 

Müllers, Erik; Silva Cascales, Helena; Burdova, Kamila; Macurek, Libor; Lindqvist, Arne. Residual Cdk1/2 activity after DNA damage promotes senescence. Aging Cell. 2017;16(3):575-584. 

Zheng, Hai-Ping; Huang, Zhi-Guang; He, Rong-Quan; Lu, Hui-Ping; Dang, Yi-Wu; Lin, Peng; Wen, Dong-Yue; Qin, Yong-Ying; Luo, Bin; Li, Xiao-Jiao; Mo, Wei-Jia; Yang, Hong; He, Yun; Chen, Gang. Integrated assessment of CDK1 upregulation in thyroid cancer. American Journal Of Translational Research. 11(12):7233-7254. 

Yasukawa, Mami; Ando, Yoshinari; Yamashita, Taro; Matsuda, Yoko; Shoji, Shisako; Morioka, Masaki Suimye; Kawaji, Hideya; Shiozawa, Kumiko; Machitani, Mitsuhiro; Abe, Takaya; Yamada, Shinji; Kaneko, Mika K; Kato, Yukinari; Furuta, Yasuhide; Kondo, Tadashi; Shirouzu, Mikako; Hayashizaki, Yoshihide; Kaneko, Shuichi; Masutomi, Kenkichi. CDK1 dependent phosphorylation of hTERT contributes to cancer progression. Nature Communications. 2020;11(1):1557. 

Shen, Peilin; He, Xuejun; Lan, Lin; Hong, Yingkai; Lin, Mingen. Identification of cell division cycle 20 as a candidate biomarker and potential therapeutic target in bladder cancer using bioinformatics analysis. Bioscience Reports. 2020;40(7) 

Suski, Jan M; Ratnayeke, Nalin; Braun, Marcin; Zhang, Tian; Strmiska, Vladislav; Michowski, Wojciech; Can, Geylani; Simoneau, Antoine; Snioch, Konrad; Cup, Mikolaj; Sullivan, Caitlin M; Wu, Xiaoji; Nowacka, Joanna; Branigan, Timothy B; Pack, Lindsey R; DeCaprio, James A; Geng, Yan; Zou, Lee; Gygi, Steven P; Walter, Johannes C; Meyer, Tobias; Sicinski, Piotr. CDC7-independent G1/S transition revealed by targeted protein degradation. Nature. 2022;605(7909):357-365.