Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA042816-25
  • Immunohistochemical staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
  • Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.
  • Western blot analysis in human cell lines HEK293 and MCF-7 using Anti-BRD2 antibody. Corresponding BRD2 RNA-seq data are presented for the same cell lines. Loading control: Anti-HSP90B1.
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Protein Description: bromodomain containing 2
Gene Name: BRD2
Alternative Gene Name: D6S113E, FSRG1, KIAA9001, NAT, RING3
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000024335: 99%, ENSRNOG00000000461: 99%
Entrez Gene ID: 6046
Uniprot ID: P25440
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen SMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGP
Gene Sequence SMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGP
Gene ID - Mouse ENSMUSG00000024335
Gene ID - Rat ENSRNOG00000000461
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation)
Datasheet Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation)
Datasheet Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation)



Citations for Anti BRD2 pAb (ATL-HPA042816 w/enhanced validation) – 2 Found
Lambert, Jean-Philippe; Picaud, Sarah; Fujisawa, Takao; Hou, Huayun; Savitsky, Pavel; Uusküla-Reimand, Liis; Gupta, Gagan D; Abdouni, Hala; Lin, Zhen-Yuan; Tucholska, Monika; Knight, James D R; Gonzalez-Badillo, Beatriz; St-Denis, Nicole; Newman, Joseph A; Stucki, Manuel; Pelletier, Laurence; Bandeira, Nuno; Wilson, Michael D; Filippakopoulos, Panagis; Gingras, Anne-Claude. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Molecular Cell. 2019;73(3):621-638.e17.  PubMed
Jostes, Sina; Nettersheim, Daniel; Fellermeyer, Martin; Schneider, Simon; Hafezi, François; Honecker, Friedemann; Schumacher, Valerie; Geyer, Matthias; Kristiansen, Glen; Schorle, Hubert. The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo. Journal Of Cellular And Molecular Medicine. 2017;21(7):1300-1314.  PubMed