Anti AMOTL1 pAb (ATL-HPA001196)

Atlas Antibodies

SKU: ATL-HPA001196-25

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Protein Description: angiomotin like 1
Gene Name: AMOTL1
Alternative Gene Name: JEAP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000013076: 82%, ENSRNOG00000008990: 32%
Entrez Gene ID: 154810
Uniprot ID: Q8IY63
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: SPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQV
• Gene Sequence: SPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQV
• Gene ID - Mouse: ENSMUSG00000013076
• Gene ID - Rat: ENSRNOG00000008990
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti AMOTL1 pAb (ATL-HPA001196) – 6 Found

Ragni, Chiara V; Diguet, Nicolas; Le Garrec, Jean-François; Novotova, Marta; Resende, Tatiana P; Pop, Sorin; Charon, Nicolas; Guillemot, Laurent; Kitasato, Lisa; Badouel, Caroline; Dufour, Alexandre; Olivo-Marin, Jean-Christophe; Trouvé, Alain; McNeill, Helen; Meilhac, Sigolène M. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nature Communications. 2017;8( 28239148):14582. 

Wei, Yiju; Yee, Patricia P; Liu, Zhijun; Zhang, Lei; Guo, Hui; Zheng, Haiyan; Anderson, Benjamin; Gulley, Melissa; Li, Wei. NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation. Embo Reports. 2020;21(12):e50642. 

Couderc, Christophe; Boin, Alizée; Fuhrmann, Laetitia; Vincent-Salomon, Anne; Mandati, Vinay; Kieffer, Yann; Mechta-Grigoriou, Fatima; Del Maestro, Laurence; Chavrier, Philippe; Vallerand, David; Brito, Isabelle; Dubois, Thierry; De Koning, Leanne; Bouvard, Daniel; Louvard, Daniel; Gautreau, Alexis; Lallemand, Dominique. AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin. Neoplasia (New York, N.y.). 2016;18(1):10-24. 

Vargas, Rebecca E; Duong, Vy Thuy; Han, Han; Ta, Albert Paul; Chen, Yuxuan; Zhao, Shiji; Yang, Bing; Seo, Gayoung; Chuc, Kimberly; Oh, Sunwoo; El Ali, Amal; Razorenova, Olga V; Chen, Junjie; Luo, Ray; Li, Xu; Wang, Wenqi. Elucidation of WW domain ligand binding specificities in the Hippo pathway reveals STXBP4 as YAP inhibitor. The Embo Journal. 2020;39(1):e102406. 

Brunner, Patrizia; Hastar, Nurcan; Kaehler, Christian; Burdzinski, Wiktor; Jatzlau, Jerome; Knaus, Petra. AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells. Molecular Biology Of The Cell. 2020;31(2):118-130. 

Zhou, Yuhang; Zhang, Jinglin; Li, Hui; Huang, Tingting; Wong, Chi Chun; Wu, Feng; Wu, Man; Weng, Nuoqing; Liu, Liping; Cheng, Alfred S L; Yu, Jun; Wong, Nathalie; Lo, Kwok Wai; Tang, Patrick M K; Kang, Wei; To, Ka Fai. AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis. Oncogene. 2020;39(22):4375-4389.