Anti ALDH1A1 pAb (ATL-HPA002123 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA002123-25
  • Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
  • Immunofluorescent staining of human cell line A549 shows localization to cytosol.
  • Western blot analysis in human cell lines A-549 and A-431 using Anti-ALDH1A1 antibody. Corresponding ALDH1A1 RNA-seq data are presented for the same cell lines. Loading control: Anti-PPIB.
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Protein Description: aldehyde dehydrogenase 1 family, member A1
Gene Name: ALDH1A1
Alternative Gene Name: ALDH1, PUMB1, RALDH1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000053279: 91%, ENSRNOG00000017619: 90%
Entrez Gene ID: 216
Uniprot ID: P00352
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen IYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGL
Gene Sequence IYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGL
Gene ID - Mouse ENSMUSG00000053279
Gene ID - Rat ENSRNOG00000017619
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.



Documents & Links for Anti ALDH1A1 pAb (ATL-HPA002123 w/enhanced validation)
Datasheet Anti ALDH1A1 pAb (ATL-HPA002123 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ALDH1A1 pAb (ATL-HPA002123 w/enhanced validation)



Citations for Anti ALDH1A1 pAb (ATL-HPA002123 w/enhanced validation) – 7 Found
Dorris, Emma R; Blackshields, Gordon; Sommerville, Gary; Alhashemi, Mohsen; Dias, Andrew; McEneaney, Victoria; Smyth, Paul; O'Leary, John J; Sheils, Orla. Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines. Cancer Biology & Therapy. 2016;17(5):526-42.  PubMed
Li, Xiangyan; Wu, Jason Boyang; Li, Qinlong; Shigemura, Katsumi; Chung, Leland W K; Huang, Wen-Chin. SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer. Oncotarget. 2016;7(11):12869-84.  PubMed
Marie, Anaïs; Leroy, Julien; Darricau, Morgane; Alfos, Serge; De Smedt-Peyrusse, Veronique; Richard, Emmanuel; Vancassel, Sylvie; Bosch-Bouju, Clementine. Preventive Vitamin A Supplementation Improves Striatal Function in 6-Hydroxydopamine Hemiparkinsonian Rats. Frontiers In Nutrition. 9( 35178422):811843.  PubMed
Szabo, Akos Z; Fong, Stephen; Yue, Lili; Zhang, Kai; Strachan, Lauren R; Scalapino, Kenneth; Mancianti, Maria Laura; Ghadially, Ruby. The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability. Stem Cells (Dayton, Ohio). 2013;31(4):786-99.  PubMed
Harper, Angelica R; Wiechmann, Allan F; Moiseyev, Gennadiy; Ma, Jian-Xing; Summers, Jody A. Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. Plos One. 10(3):e0122008.  PubMed
Taylor, Bethany; Rice, Alexandra; Nicholson, Andrew G; Hind, Matthew; Dean, Charlotte H. Mechanism of lung development in the aetiology of adult congenital pulmonary airway malformations. Thorax. 2020;75(11):1001-1003.  PubMed
Canesin, Giacomo; Maggio, Valentina; Palominos, Macarena; Stiehm, Anna; Contreras, Hector R; Castellón, Enrique A; Morote, Juan; Paciucci, Rosanna; Maitland, Norman J; Bjartell, Anders; Hellsten, Rebecka. STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population. Scientific Reports. 2020;10(1):13958.  PubMed