Anti ACO2 pAb (ATL-HPA001097 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA001097-25

Protein Description: aconitase 2, mitochondrial
Gene Name: ACO2
Alternative Gene Name: ACONM
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000022477: 97%, ENSRNOG00000024128: 97%
Entrez Gene ID: 50
Uniprot ID: Q99798
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: GKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEG
• Gene Sequence: GKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEG
• Gene ID - Mouse: ENSMUSG00000022477
• Gene ID - Rat: ENSRNOG00000024128
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti ACO2 pAb (ATL-HPA001097 w/enhanced validation) – 6 Found

Stumpf, Sina K; Berghoff, Stefan A; Trevisiol, Andrea; Spieth, Lena; Düking, Tim; Schneider, Lennart V; Schlaphoff, Lennart; Dreha-Kulaczewski, Steffi; Bley, Annette; Burfeind, Dinah; Kusch, Kathrin; Mitkovski, Miso; Ruhwedel, Torben; Guder, Philipp; Röhse, Heiko; Denecke, Jonas; Gärtner, Jutta; Möbius, Wiebke; Nave, Klaus-Armin; Saher, Gesine. Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica. 2019;138(1):147-161. 

Medina-Carbonero, Marta; Sanz-Alcázar, Arabela; Britti, Elena; Delaspre, Fabien; Cabiscol, Elisa; Ros, Joaquim; Tamarit, Jordi. Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations. Cellular And Molecular Life Sciences : Cmls. 2022;79(2):74. 

Cantu, David; Fulton, Ruth E; Drechsel, Derek A; Patel, Manisha. Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂. Journal Of Neurochemistry. 2011;118(1):79-92. 

Ilgen, Peter; Stoldt, Stefan; Conradi, Lena-Christin; Wurm, Christian Andreas; Rüschoff, Josef; Ghadimi, B Michael; Liersch, Torsten; Jakobs, Stefan. STED super-resolution microscopy of clinical paraffin-embedded human rectal cancer tissue. Plos One. 9(7):e101563. 

Latonen, Leena; Afyounian, Ebrahim; Jylhä, Antti; Nättinen, Janika; Aapola, Ulla; Annala, Matti; Kivinummi, Kati K; Tammela, Teuvo T L; Beuerman, Roger W; Uusitalo, Hannu; Nykter, Matti; Visakorpi, Tapio. Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression. Nature Communications. 2018;9(1):1176. 

Mirhadi, Shideh; Zhang, Wen; Pham, Nhu-An; Karimzadeh, Fereshteh; Pintilie, Melania; Tong, Jiefei; Taylor, Paul; Krieger, Jonathan; Pitcher, Bethany; Sykes, Jenna; Wybenga-Groot, Leanne; Fladd, Christopher; Xu, Jing; Wang, Tao; Cabanero, Michael; Li, Ming; Weiss, Jessica; Sakashita, Shingo; Zaslaver, Olga; Yu, Man; Caudy, Amy A; St-Pierre, Julie; Hawkins, Cynthia; Kislinger, Thomas; Liu, Geoffrey; Shepherd, Frances A; Tsao, Ming-Sound; Moran, Michael F. Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non-Small Cell Lung Cancer. Molecular Cancer Research : Mcr. 2023;21(1):36-50.