Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA007569-25
  • Immunohistochemical staining of human cerebellum, kidney, liver and testis using Anti-ACAT1 antibody HPA007569 (A) shows similar protein distribution across tissues to independent antibody HPA004428 (B).
  • Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
  • Western blot analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ACAT1 antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
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Protein Description: acetyl-CoA acetyltransferase 1
Gene Name: ACAT1
Alternative Gene Name: ACAT, THIL
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032047: 80%, ENSRNOG00000007862: 81%
Entrez Gene ID: 38
Uniprot ID: P24752
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen NEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMV
Gene Sequence NEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMV
Gene ID - Mouse ENSMUSG00000032047
Gene ID - Rat ENSRNOG00000007862
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation)
Datasheet Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation)
Datasheet Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation)



Citations for Anti ACAT1 pAb (ATL-HPA007569 w/enhanced validation) – 5 Found
Stadler, Charlotte; Hjelmare, Martin; Neumann, Beate; Jonasson, Kalle; Pepperkok, Rainer; Uhlén, Mathias; Lundberg, Emma. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. Journal Of Proteomics. 2012;75(7):2236-51.  PubMed
Martinez-Outschoorn, Ubaldo E; Lin, Zhao; Whitaker-Menezes, Diana; Howell, Anthony; Lisanti, Michael P; Sotgia, Federica. Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells. Cell Cycle (Georgetown, Tex.). 2012;11(21):3956-63.  PubMed
Martinez-Outschoorn, Ubaldo E; Lin, Zhao; Whitaker-Menezes, Diana; Howell, Anthony; Sotgia, Federica; Lisanti, Michael P. Ketone body utilization drives tumor growth and metastasis. Cell Cycle (Georgetown, Tex.). 2012;11(21):3964-71.  PubMed
Chang, Howard T; Olson, Lawrence Karl; Schwartz, Kenneth A. Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy. Nutrition & Metabolism. 2013;10(1):47.  PubMed
Andersson, Sandra; Konrad, Anna; Ashok, Nikhil; Pontén, Fredrik; Hober, Sophia; Asplund, Anna. Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection. The Journal Of Histochemistry And Cytochemistry : Official Journal Of The Histochemistry Society. 2013;61(11):773-84.  PubMed