"Linking Ubiquitin Research to Drug Discovery"

Ubiquigent - Antibodies

Ubiquigent offers antibodies against full length or partial proteins, from the ubiquitin proteasome (UPS) pathway; these include E2 conjugating enzymes, E3 ligases, DUBs, ubiquitin binding proteins substrates and conjugate antibodies. The anti-polyubiquitylated conjugates mAb (FK1) and the anti-mono and polyubiquitylated conjugates mAb (FK2) have been extensively characterized and can be used to demonstrate the specific recognition of polyubiquitylated and mono and polyubiquitylated protein conjugates respectively, but show no reactivity with free ubiquitin. Ubiquigent also offer a number of kinase antibodies, Like ubiquitylation, phosphorylation is a reversible post-translational modification. Abnormal protein phosphorylation is a cause or consequence of disease, including cancers, diabetes and inflammatory disease, while defects in genes that encode protein kinases and phosphatases underlie a number of inherited disorders. Around 500 protein kinases are encoded in the human genome and they account for around 25% of the molecular targets currently being pursued by drug discovery companies. It is becoming increasingly apparent that there is significant cross-talk between these two key intracellular systems; phosphorylation and ubiquitylation.

Catalog Number	Product Name	Size	Datasheet	Clone	Application	Clonality	Host	Reactivity
UBI-68-0001-100	Anti Mouse TNFAIP3 Interacting Protein 1 (TNIP1/ABIN1) pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Mouse
UBI-68-0002-100	Anti Human TNFAIP3 Interacting Protein 1 (TNIP1/ABIN1) pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0003-100	Anti Cullin Associated And Neddylation Dissociated 1 (CAND1) Human residues 5-245 pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0004-100	Anti Cullin 3 (CUL3) Human residues 554-768 pAb (Sheep, Affinity Purified)	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0005-100	Anti Cullin 5 (CUL5) Human residues 577-689 pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0006-100	Anti CYLD Lysine 63 Deubiquitinase (CYLD) pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0007-100	Anti Defective In Cullin Neddylation 1 Domain Containing 3 (DCUN1D3/DCNL3) Human full length pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0008-100	Anti Defective In Cullin Neddylation 1 Domain Containing 4 (DCUN1D4/DCNL4) Human full length pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0009-100	Anti Defective In Cullin Neddylation 1 Domain Containing 5 (DCUN1D5/DCNL5) Mouse full length pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Mouse
UBI-68-0010-100	Anti Defective In Cullin Neddylation 1 Domain Containing 5 (DCUN1D5/DCNL5) Human full length pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0011-100	Anti Fas Associated Factor 1 (FAF1) pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0012-100	Anti RANBP2-Type And C3HC4-Type Zinc Finger Containing 1 (RBCK1/HOIL1) pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0013-100	Anti Ring Finger Protein 31 (RNF31/HOIP) pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0014-100	NEMO (human; full length), pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0015-100	Optineurin (human; full length), pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0016-100	OTUB1 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0017-100	OTULIN (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0018-100	Parkin (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0019-100	PINK1 (human; residues 175 – 250), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0020-100	RNF7 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0021-100	SHARPIN (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0022-100	TRAF6 (mouse; full length), pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Mouse
UBI-68-0023-100	TRIAD1 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0024-100	TRIM65 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0025-100	UBE2M (mouse; full length), pAb	100 ug	Datasheet		WB, DB	Polyclonal	Sheep	Mouse
UBI-68-0026-100	UBE2T (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0027-100	UBXD7 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0028-100	USP11 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0029-100	USP15 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0030-100	PKB Alpha (human; residues 1-147) pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0031-100	PKB Beta (mouse; residues 455-469) pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Mouse
UBI-68-0032-100	PKB Gamma (human; residues 116-127) pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0033-100	SGK1 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0034-100	Anti Serum/Glucocorticoid Regulated Kinase 2 (SGK2) Human residues 412-431 pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0035-100	Anti Serum/Glucocorticoid Regulated Kinase 2 (SGK2) Human residues 333-346 pAb (Sheep, Affinity Purified)	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0036-100	SGK3 (human; full length), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0037-100	FOXO3A pSer7 (mouse; residues 3 - 11), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0038-100	FOXO3A pSer294 (human; residues 289 - 298), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0039-100	FOXO3A pSer344 (mouse; residues 339 - 348), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0040-100	MAPK15 (human; full length), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0041-100	Anti Protein Phosphatase 1 Regulatory Subunit 12A (PPP1R12A/MYPT1) Human residues 728-838 pAb (Sheep, Affinity Purified)	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0042-100	MYPT1 pThr34 (mouse; residues 27 - 41) pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0043-100	MYPT1 pSer445 (mouse; residues 437 - 452) pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0044-100	MYPT1 pSer472 (mouse; residues 466-478) pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0045-100	MYPT1 pSer554 (mouse; residues 547-618) pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0046-100	MYPT1 pSer909 (mouse; residues 903-917) pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Mouse
UBI-68-0047-100	MYPT2 (human; residues 350-450), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0048-100	MYPT3 (human; full length), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0049-100	IKK Beta (human; full length) pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0050-100	IKK Epsilon (human; residues 701-716) pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0051-100	IKK Epsilon (mouse; residues 702-717) pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Mouse
UBI-68-0052-100	IKK Epsilon pSer172 (human; residues 168–177) pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0053-100	TBK1 (human; full length), pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0054-100	TBK1 pSer172 (human; residues 168 – 177), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0055-100	AMPK alpha 2 (human; residues 352 – 366), pAb	100 ug	Datasheet		IP, WB	Polyclonal	Sheep	Human
UBI-68-0056-100	Parkin pSer65 (human; residues 60 - 72), pAb	100 ug	Datasheet		WB	Polyclonal	Sheep	Human
UBI-68-0057-100	PINK1 pThr257 (human; residues 250 - 262), pAb	100 ug	Datasheet		IP	Polyclonal	Sheep	Human
UBI-68-0111-500	Polyubiquitylated conjugates, mAb (FK1)	500 ug	Datasheet	FK1	WB	Monoclonal	Mouse	Human
UBI-68-0121-500	Mono and Polyubiquitylated conjugates, mAb (FK2)	500 ug	Datasheet	FK2	ChIP, WB	Monoclonal	Mouse	Human
UBI-68-0122-025	Anti Mono and Polyubiquitylated conjugates mAb (clone FK2, HRP-conjugated)	100 ug	Datasheet	FK2	ChIP	Monoclonal	Mouse
UBI-68-0122-025	Anti Mono and Polyubiquitylated conjugates mAb (clone FK2, HRP-conjugated)	25 ug	Datasheet	FK2	ChIP	Monoclonal	Mouse	Human
UBI-68-0123-025	Anti Mono and Polyubiquitylated conjugates mAb (clone FK2, Biotin-conjugated)	100 ug	Datasheet	FK2	ChIP	Monoclonal	Mouse
UBI-68-0123-025	Anti Mono and Polyubiquitylated conjugates mAb (clone FK2, Biotin-conjugated)	25 ug	Datasheet	FK2	ChIP	Monoclonal	Mouse	Human