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Ubiquitin Chains - Why To Use Ubiquigent Reagents
● Fully annotated protein sequence
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Validation and Experimental Utility of the E2scan™ Kit version 2
"Linking Ubiquitin Research to Drug Discovery"
Ubiquigent - HTS Assay
Many enzymes from across the ubiquitin system have been identified as potential drug discovery targets; see our Therapeutic Area pages for more information. With reference to these therapeutic area opportunities Ubiquigent’s high-throughput screening (HTS) compatible assay kits are developed and optimized for your convenience and are validated specifically for HTS applications. Everything that you require is provided in the kit: enzymes, substrates, buffers, protocols, and access to ongoing support. Kits are available in 5,000 and 30,000 data point sizes, larger kits (for 1million+ data points have been and can be supplied too).
Ubiquitin also offer customization to fit your precise needs; number of data points required, budget, assay design, configuration and logistics or specialist therapeutic area requirements. E2 ubiquitin conjugating enzyme HTS assay kits Ubiquigent have an extensive collection of E2 enzymes (click here for details) and have developed a selection of these into HTS-compatible assays (Homogenous Time-Resolved Fluorescence (HTRF®)-based) for use either directly in a screen or for deconvoluting ‘hits’ derived from an E3 HTS assay screening campaign.
E3 ubiquitin ligase enzyme HTS assay kits The table below lists HTRF®-based HTS-compatible E3 ubiquitin ligase assays that Ubiquigent developed initially under contract for major pharmaceutical clients through our Custom Assay Development program and that are now available for general sale.
Catalog Number | Product Name | Size | Datasheet |
UBI-70-1010 | IDOL-catalysed LDLR substrate ubiquitylation assay kit | 1 Kit | Datasheet |
UBI-70-1020 | IDOL-catalysed MRLC substrate ubiquitylation assay kit | 1 Kit | Datasheet |
UBI-70-1030 | IDOL-catalysed autoubiquitylation assay kit | 1 Kit | Datasheet |
UBI-70-1040 | CHIP-catalysed autoubiquitylation assay kit | 1 Kit | Datasheet |