MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.  Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Product Specifications
Application FC
Reactivity Mouse
Conjugation APC
Immunogen mouse 2W1S
Peptide Sequence EAWGALANWAVDSA
Class Class II
Sequence Location 52-68
MHC Allele I-Ab

Documents & Links for T-Select I-Ab mouse 2W1S Tetramer-APC (Discontinued See Catalog Number: MBL-TC-M722-2)
Datasheet T-Select I-Ab mouse 2W1S Tetramer-APC Datasheet

Documents & Links for T-Select I-Ab mouse 2W1S Tetramer-APC (Discontinued See Catalog Number: MBL-TC-M722-2)
Datasheet T-Select I-Ab mouse 2W1S Tetramer-APC Datasheet
Citations for T-Select I-Ab mouse 2W1S Tetramer-APC (Discontinued See Catalog Number: MBL-TC-M722-2) – 1 Found
Liao, Ting-Yu Angela; Lau, Alice; Joseph, Sunil; Hytönen, Vesa; Hmama, Zakaria. Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System. Plos One. 10(12):e0145833.  PubMed