Anti TTR pAb (ATL-HPA002550)

Atlas Antibodies

Catalog No.: ATL-HPA002550-100

Protein Description: transthyretin
Gene Name: TTR
Alternative Gene Name: CTS, CTS1, HsT2651, PALB
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000061808: 81%, ENSRNOG00000016275: 83%
Entrez Gene ID: 7276
Uniprot ID: P02766
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: GTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
• Gene Sequence: GTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
• Gene ID - Mouse: ENSMUSG00000061808
• Gene ID - Rat: ENSRNOG00000016275
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti TTR pAb (ATL-HPA002550) – 5 Found

Galant, Natalie J; Bugyei-Twum, Antoinette; Rakhit, Rishi; Walsh, Patrick; Sharpe, Simon; Arslan, Pharhad Eli; Westermark, Per; Higaki, Jeffrey N; Torres, Ronald; Tapia, José; Chakrabartty, Avijit. Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses. Scientific Reports. 2016;6( 27122057):25080. 

Noborn, Fredrik; O'Callaghan, Paul; Hermansson, Erik; Zhang, Xiao; Ancsin, John B; Damas, Ana M; Dacklin, Ingrid; Presto, Jenny; Johansson, Jan; Saraiva, Maria J; Lundgren, Erik; Kisilevsky, Robert; Westermark, Per; Li, Jin-Ping. Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2011;108(14):5584-9. 

Kato, Bernet S; Nicholson, George; Neiman, Maja; Rantalainen, Mattias; Holmes, Chris C; Barrett, Amy; Uhlén, Mathias; Nilsson, Peter; Spector, Tim D; Schwenk, Jochen M. Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. Proteome Science. 2011;9( 22093360):73. 

Liu, T; Zhang, B; Jin, X; Wang, W; Lee, J; Li, J; Yuan, H; Cheng, X. Ophthalmic manifestations in a Chinese family with familial amyloid polyneuropathy due to a TTR Gly83Arg mutation. Eye (London, England). 2014;28(1):26-33. 

Månberg, Anna; Bradley, Frideborg; Qundos, Ulrika; Guthrie, Brandon L; Birse, Kenzie; Noël-Romas, Laura; Lindskog, Cecilia; Bosire, Rose; Kiarie, James; Farquhar, Carey; Burgener, Adam D; Nilsson, Peter; Broliden, Kristina. A High-throughput Bead-based Affinity Assay Enables Analysis of Genital Protein Signatures in Women At Risk of HIV Infection. Molecular & Cellular Proteomics : Mcp. 2019;18(3):461-476.