Anti PTPN12 pAb (ATL-HPA007097)

Atlas Antibodies

Catalog No.: ATL-HPA007097-25

Protein Description: protein tyrosine phosphatase, non-receptor type 12
Gene Name: PTPN12
Alternative Gene Name: PTP-PEST, PTPG1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000028771: 63%, ENSRNOG00000013135: 64%
Entrez Gene ID: 5782
Uniprot ID: Q05209
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: SVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAAT
• Gene Sequence: SVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAAT
• Gene ID - Mouse: ENSMUSG00000028771
• Gene ID - Rat: ENSRNOG00000013135
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti PTPN12 pAb (ATL-HPA007097) – 3 Found

Harris, I S; Blaser, H; Moreno, J; Treloar, A E; Gorrini, C; Sasaki, M; Mason, J M; Knobbe, C B; Rufini, A; Hallé, M; Elia, A J; Wakeham, A; Tremblay, M L; Melino, G; Done, S; Mak, T W. PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling. Oncogene. 2014;33(8):1047-54. 

Cao, Xun; Chen, Yan-Zhen; Luo, Ruo-Zhen; Zhang, Lin; Zhang, Song-Liang; Zeng, Jun; Jiang, Yu-Chuan; Han, Yu-Jing; Wen, Zhe-Sheng. Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer. Oncotarget. 2015;6(13):11704-13. 

Weidemann, Sören A; Sauer, Charlotte; Luebke, Andreas M; Möller-Koop, Christina; Steurer, Stefan; Hube-Magg, Claudia; Büscheck, Franziska; Höflmayer, Doris; Tsourlakis, Maria Christina; Clauditz, Till S; Simon, Ronald; Sauter, Guido; Göbel, Cosima; Lebok, Patrick; Dum, David; Fraune, Christoph; Kind, Simon; Minner, Sarah; Izbicki, Jakob; Schlomm, Thorsten; Huland, Hartwig; Heinzer, Hans; Burandt, Eike; Haese, Alexander; Graefen, Markus; Heumann, Asmus. High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer. Bmc Cancer. 2019;19(1):944.