Anti IARS2 pAb (ATL-HPA024212 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA024212-25

Protein Description: isoleucyl-tRNA synthetase 2, mitochondrial
Gene Name: IARS2
Alternative Gene Name: FLJ10326
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000026618: 79%, ENSRNOG00000002368: 77%
Entrez Gene ID: 55699
Uniprot ID: Q9NSE4
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: NVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYV
• Gene Sequence: NVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYV
• Gene ID - Mouse: ENSMUSG00000026618
• Gene ID - Rat: ENSRNOG00000002368
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti IARS2 pAb (ATL-HPA024212 w/enhanced validation) – 2 Found

Perli, Elena; Giordano, Carla; Tuppen, Helen A L; Montopoli, Monica; Montanari, Arianna; Orlandi, Maurizia; Pisano, Annalinda; Catanzaro, Daniela; Caparrotta, Laura; Musumeci, Beatrice; Autore, Camillo; Morea, Veronica; Di Micco, Patrizio; Campese, Antonio F; Leopizzi, Martina; Gallo, Pietro; Francisci, Silvia; Frontali, Laura; Taylor, Robert W; d'Amati, Giulia. Isoleucyl-tRNA synthetase levels modulate the penetrance of a homoplasmic m.4277T>C mitochondrial tRNA(Ile) mutation causing hypertrophic cardiomyopathy. Human Molecular Genetics. 2012;21(1):85-100. 

Vona, Barbara; Maroofian, Reza; Bellacchio, Emanuele; Najafi, Maryam; Thompson, Kyle; Alahmad, Ahmad; He, Langping; Ahangari, Najmeh; Rad, Abolfazl; Shahrokhzadeh, Sima; Bahena, Paulina; Mittag, Falk; Traub, Frank; Movaffagh, Jebrail; Amiri, Nafise; Doosti, Mohammad; Boostani, Reza; Shirzadeh, Ebrahim; Haaf, Thomas; Diodato, Daria; Schmidts, Miriam; Taylor, Robert W; Karimiani, Ehsan Ghayoor. Expanding the clinical phenotype of IARS2-related mitochondrial disease. Bmc Medical Genetics. 2018;19(1):196.