Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA017991-25
  • Immunohistochemical staining of human Fallopian tube shows strong cytoplasmic and membranous positivity in glandular cells.
  • Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
  • Western blot analysis in human cell line A-431 and human cell line CACO-2.
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Protein Description: frizzled class receptor 6
Gene Name: FZD6
Alternative Gene Name: Hfz6
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000107137: 55%, ENSRNOG00000004660: 62%
Entrez Gene ID: 8323
Uniprot ID: O60353
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen TSTGATANHGTSAVAITSHDYLGQETLTEIQTSPETSMREVKADGASTPRLREQDCGEPASPAASISRLSGEQVDGKGQAGSVSESARSEGRISPKSDITDTGLAQSNNLQVPSSSEPSSLKGSTSLLVHPVS
Gene Sequence TSTGATANHGTSAVAITSHDYLGQETLTEIQTSPETSMREVKADGASTPRLREQDCGEPASPAASISRLSGEQVDGKGQAGSVSESARSEGRISPKSDITDTGLAQSNNLQVPSSSEPSSLKGSTSLLVHPVS
Gene ID - Mouse ENSMUSG00000107137
Gene ID - Rat ENSRNOG00000004660
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation)
Datasheet Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation)
Datasheet Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation)



Citations for Anti FZD6 pAb (ATL-HPA017991 w/enhanced validation) – 2 Found
Chen, Zhenzhen; Gao, Yanfeng; Yao, Lintong; Liu, Yating; Huang, Lan; Yan, Zhongyi; Zhao, Wenshan; Zhu, Pingping; Weng, Haibo. LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation. Oncogene. 2018;37(23):3098-3112.  PubMed
Strakova, Katerina; Kowalski-Jahn, Maria; Gybel, Tomas; Valnohova, Jana; Dhople, Vishnu M; Harnos, Jakub; Bernatik, Ondrej; Ganji, Ranjani Sri; Zdrahal, Zbynek; Mulder, Jan; Lindskog, Cecilia; Bryja, Vitezslav; Schulte, Gunnar. Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization. The Journal Of Biological Chemistry. 2018;293(48):18477-18493.  PubMed