Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA006028-25
  • Immunohistochemistry analysis in human heart muscle and liver tissues using HPA006028 antibody. Corresponding FHL2 RNA-seq data are presented for the same tissues.
  • Immunofluorescent staining of human cell line U-2 OS shows localization to actin filaments & focal adhesion sites.
  • Western blot analysis in human cell line U-2 OS.
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Protein Description: four and a half LIM domains 2
Gene Name: FHL2
Alternative Gene Name: DRAL, SLIM3
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000008136: 89%, ENSRNOG00000016866: 89%
Entrez Gene ID: 2274
Uniprot ID: Q14192
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Immunogen RFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS
Gene Sequence RFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS
Gene ID - Mouse ENSMUSG00000008136
Gene ID - Rat ENSRNOG00000016866
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation)
Datasheet Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation)
Datasheet Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation)



Citations for Anti FHL2 pAb (ATL-HPA006028 w/enhanced validation) – 6 Found
Nakazawa, Naotaka; Sathe, Aneesh R; Shivashankar, G V; Sheetz, Michael P. Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2016;113(44):E6813-E6822.  PubMed
Maier, Jasmin I; Rogg, Manuel; Helmstädter, Martin; Sammarco, Alena; Walz, Gerd; Werner, Martin; Schell, Christoph. A Novel Model for Nephrotic Syndrome Reveals Associated Dysbiosis of the Gut Microbiome and Extramedullary Hematopoiesis. Cells. 2021;10(6)  PubMed
Basu, Himanish; Pekkurnaz, Gulcin; Falk, Jill; Wei, Wei; Chin, Morven; Steen, Judith; Schwarz, Thomas L. FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply. The Journal Of Cell Biology. 2021;220(10)  PubMed
Pontén, Fredrik; Gry, Marcus; Fagerberg, Linn; Lundberg, Emma; Asplund, Anna; Berglund, Lisa; Oksvold, Per; Björling, Erik; Hober, Sophia; Kampf, Caroline; Navani, Sanjay; Nilsson, Peter; Ottosson, Jenny; Persson, Anja; Wernérus, Henrik; Wester, Kenneth; Uhlén, Mathias. A global view of protein expression in human cells, tissues, and organs. Molecular Systems Biology. 5( 20029370):337.  PubMed
Stadler, Charlotte; Hjelmare, Martin; Neumann, Beate; Jonasson, Kalle; Pepperkok, Rainer; Uhlén, Mathias; Lundberg, Emma. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. Journal Of Proteomics. 2012;75(7):2236-51.  PubMed
Stadler, Charlotte; Rexhepaj, Elton; Singan, Vasanth R; Murphy, Robert F; Pepperkok, Rainer; Uhlén, Mathias; Simpson, Jeremy C; Lundberg, Emma. Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nature Methods. 2013;10(4):315-23.  PubMed