Anti FBXW8 pAb (ATL-HPA038851 w/enhanced validation)

Atlas Antibodies

SKU: ATL-HPA038851-25

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Protein Description: F-box and WD repeat domain containing 8
Gene Name: FBXW8
Alternative Gene Name: FBW6, FBW8, FBX29, FBXO29
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032867: 89%, ENSRNOG00000001126: 87%
Entrez Gene ID: 26259
Uniprot ID: Q8N3Y1
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: KLIFQECRAKEHMLQTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSGDVRVWDTRTWDYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAA
• Gene Sequence: KLIFQECRAKEHMLQTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSGDVRVWDTRTWDYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAA
• Gene ID - Mouse: ENSMUSG00000032867
• Gene ID - Rat: ENSRNOG00000001126
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti FBXW8 pAb (ATL-HPA038851 w/enhanced validation) – 2 Found

Fahlbusch, Fabian B; Dawood, Yousif; Hartner, Andrea; Menendez-Castro, Carlos; Nögel, Stephanie C; Tzschoppe, Anja; Schneider, Holm; Strissel, Pamela; Beckmann, Matthias W; Schleussner, Ekkehard; Ruebner, Matthias; Dörr, Helmuth G; Schild, Ralf L; Rascher, Wolfgang; Dötsch, Jörg. Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?. The Journal Of Maternal-Fetal & Neonatal Medicine : The Official Journal Of The European Association Of Perinatal Medicine, The Federation Of Asia And Oceania Perinatal Societies, The International Society Of Perinatal Obstetricians. 2012;25(11):2209-15. 

Halbach, Melanie Vanessa; Stehning, Tanja; Damrath, Ewa; Jendrach, Marina; Şen, Nesli Ece; Başak, A Nazlı; Auburger, Georg. Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated. Plos One. 10(3):e0121089.