Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA001600-25
  • Immunohistochemical staining of human appendix shows moderate nuclear positivity in lymphoid tissue.
  • Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
  • Western blot analysis in control (vector only transfected HEK293T lysate) and ELK3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401602).
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Protein Description: ELK3, ETS-domain protein (SRF accessory protein 2)
Gene Name: ELK3
Alternative Gene Name: ERP, NET, SAP2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000008398: 88%, ENSRNOG00000004367: 91%
Entrez Gene ID: 2004
Uniprot ID: P41970
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC, ChIP-Exo-Seq
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen KNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKASPEGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRFVTNKTDKHVTR
Gene Sequence KNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKASPEGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRFVTNKTDKHVTR
Gene ID - Mouse ENSMUSG00000008398
Gene ID - Rat ENSRNOG00000004367
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation)
Datasheet Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation)
Datasheet Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation)



Citations for Anti ELK3 pAb (ATL-HPA001600 w/enhanced validation) – 4 Found
Semenchenko, Kostyantyn; Wasylyk, Christine; Cheung, Henry; Tourrette, Yves; Maas, Peter; Schalken, Jack A; van der Pluijm, Gabri; Wasylyk, Bohdan. XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice. Plos One. 11(7):e0159531.  PubMed
Zhao, Qiuyan; Ren, Yingchun; Xie, Haoran; Yu, Lanting; Lu, Jiawei; Jiang, Weiliang; Xiao, Wenqin; Zhu, Zhonglin; Wan, Rong; Li, Baiwen. ELK3 Mediated by ZEB1 Facilitates the Growth and Metastasis of Pancreatic Carcinoma by Activating the Wnt/β-Catenin Pathway. Frontiers In Cell And Developmental Biology. 9( 34409034):700192.  PubMed
Liu, Zhendong; Ren, Zhishuai; Zhang, Cheng; Qian, Rongjun; Wang, Hongbo; Wang, Jialin; Zhang, Wang; Liu, Binfeng; Lian, Xiaoyu; Wang, Yanbiao; Guo, Yuqi; Gao, Yanzheng. ELK3: A New Molecular Marker for the Diagnosis and Prognosis of Glioma. Frontiers In Oncology. 11( 34976781):608748.  PubMed
Robertson, E Douglas; Wasylyk, Christine; Ye, Tao; Jung, Alain C; Wasylyk, Bohdan. The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. Plos One. 9(11):e113050.  PubMed