Anti DDX3X pAb (ATL-HPA001648 w/enhanced validation)

Atlas Antibodies

SKU: ATL-HPA001648-25

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Protein Description: DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
Gene Name: DDX3X
Alternative Gene Name: DBX, DDX14, DDX3, HLP2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000000787: 97%, ENSRNOG00000023383: 97%
Entrez Gene ID: 1654
Uniprot ID: O00571
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: LNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPV
• Gene Sequence: LNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPV
• Gene ID - Mouse: ENSMUSG00000000787
• Gene ID - Rat: ENSRNOG00000023383
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti DDX3X pAb (ATL-HPA001648 w/enhanced validation) – 7 Found

Kamelgarn, Marisa; Chen, Jing; Kuang, Lisha; Arenas, Alexandra; Zhai, Jianjun; Zhu, Haining; Gal, Jozsef. Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. Biochimica Et Biophysica Acta. 2016;1862(10):2004-14. 

Hoye, Mariah L; Calviello, Lorenzo; Poff, Abigail J; Ejimogu, Nna-Emeka; Newman, Carly R; Montgomery, Maya D; Ou, Jianhong; Floor, Stephen N; Silver, Debra L. Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model. Elife. 2022;11( 35762573) 

Mulder, Jan; Björling, Erik; Jonasson, Kalle; Wernérus, Henrik; Hober, Sophia; Hökfelt, Tomas; Uhlén, Mathias. Tissue profiling of the mammalian central nervous system using human antibody-based proteomics. Molecular & Cellular Proteomics : Mcp. 2009;8(7):1612-22. 

Stadler, Charlotte; Hjelmare, Martin; Neumann, Beate; Jonasson, Kalle; Pepperkok, Rainer; Uhlén, Mathias; Lundberg, Emma. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. Journal Of Proteomics. 2012;75(7):2236-51. 

Hagerstrand, Daniel; Tong, Alexander; Schumacher, Steven E; Ilic, Nina; Shen, Rhine R; Cheung, Hiu Wing; Vazquez, Francisca; Shrestha, Yashaswi; Kim, So Young; Giacomelli, Andrew O; Rosenbluh, Joseph; Schinzel, Anna C; Spardy, Nicole A; Barbie, David A; Mermel, Craig H; Weir, Barbara A; Garraway, Levi A; Tamayo, Pablo; Mesirov, Jill P; Beroukhim, Rameen; Hahn, William C. Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discovery. 2013;3(9):1044-57. 

Hayes, Lindsey R; Duan, Lauren; Bowen, Kelly; Kalab, Petr; Rothstein, Jeffrey D. C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import. Elife. 2020;9( 32119645) 

Lennox, Ashley L; Hoye, Mariah L; Jiang, Ruiji; Johnson-Kerner, Bethany L; Suit, Lindsey A; Venkataramanan, Srivats; Sheehan, Charles J; Alsina, Fernando C; Fregeau, Brieana; Aldinger, Kimberly A; Moey, Ching; Lobach, Iryna; Afenjar, Alexandra; Babovic-Vuksanovic, Dusica; Bézieau, Stéphane; Blackburn, Patrick R; Bunt, Jens; Burglen, Lydie; Campeau, Philippe M; Charles, Perrine; Chung, Brian H Y; Cogné, Benjamin; Curry, Cynthia; D'Agostino, Maria Daniela; Di Donato, Nataliya; Faivre, Laurence; Héron, Delphine; Innes, A Micheil; Isidor, Bertrand; Keren, Boris; Kimball, Amy; Klee, Eric W; Kuentz, Paul; Küry, Sébastien; Martin-Coignard, Dominique; Mirzaa, Ghayda; Mignot, Cyril; Miyake, Noriko; Matsumoto, Naomichi; Fujita, Atsushi; Nava, Caroline; Nizon, Mathilde; Rodriguez, Diana; Blok, Lot Snijders; Thauvin-Robinet, Christel; Thevenon, Julien; Vincent, Marie; Ziegler, Alban; Dobyns, William; Richards, Linda J; Barkovich, A James; Floor, Stephen N; Silver, Debra L; Sherr, Elliott H. Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. 2020;106(3):404-420.e8.