Anti Nuclear Pore Glycoprotein p62 (NUP62) mAb (Clone 2A)

Cosmo Bio LTD

Catalog No: BAM-70-305EX

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Application: ELISA, IF, ICC, WB, IP 
Clonality: Monoclonal 
Host: Rat 
Purification: IgG 
Reactivity: Monkey, Human 
The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nucleoporins

are the main components of the NPC in eukaryotic cells. Nup (Nucleoporin) 62 (522 aa, 53 kDa) is a member of the

FG-repeat containing nucleoporins and is localized to the NPC central plug. Nup62 associates with the importin

alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Predicted to

contain about 10 N-acetylglucosamine side chain . Application: Applications

1. Western blotting (1/500 ~1/2,000 dilution)

2. Immunoprecipitation (assay dependent)

3. Immunofluorescece / Immunocytochemistry (1/400)

4. ELISA (assay dependent)

5. When this antibody was micro-injected into the cytoplasm of the HeLa cells, it accumulates into the nuclear

pores as examined by immunofluorescence staining..

Immunogen: Recombinant human Nup62 (aa 1-300) (GST-Nup62-His)

Specificity: Specific to human (HeLa cells) and simian (Cos cells). The antibody did not react with mouse.