Anti Importin Subunit Alpha-3 (KPNA4/Qip1) mAb (Clone 3D10)

Cosmo Bio LTD

Catalog No: BAM-70-325-EX

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Application: WB, ELISA 
Clonality: Monoclonal 
Host: Rat 
Purification: IgG 
Reactivity: Human, Monkey, Mouse, Rat, Hamster, Dog, Bovine 
Importinα proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importinαproteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin β.Several importinα isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importinα3 (KPNA4, Qip1) is amember of the importinα family of proteins belonging to the Qip1 subfamily. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.