Glycation Related Research Series
AGEs production inhibitory effect confirmed in vitro !
When sugars coexist with proteins in vivo, they modify and crosslink lysine and arginine residues in proteins, altering the three-dimensional structure of proteins and greatly affecting their activity and physical properties. This reaction is called the saccharification reaction (Glycation) or the Maillard reaction, and leads to advanced glycation end products (AGEs) through the early reaction that produces Amadori rearrangement products and reactions such as oxidation, dehydration, and condensation. divided into late reactions.
Cosmo Bio sells a kit that allows you to follow these saccharification reactions in a cell-free and non-enzymatic manner. All kits use 96-well plates. Please use it for the development of anti-glycation materials in the development of functional foods and cosmetics.
| kit | Measuring method | Usage | |
| 1 | Collagen Anti-Glycation Assay Kit Glucose/Fructose |
Glycation reaction that occurs when glucose or fructose is added to collagen gel is monitored by fluorescence. | Screening of anti-glycation substances, development of anti-glycation materials in the development of functional foods and cosmetics |
| The assay period is 10 days to 4 weeks. | |||
| (Catalog No.: PMC-AK70) | |||
| 2 | Collagen Anti-Glycation Assay Kit Glyceraldehyde |
The saccharification reaction that occurs when glyceraldehyde is added to collagen gel is monitored by fluorescence. | Screening of anti-glycation substances, development of anti-glycation materials in the development of functional foods and cosmetics |
| Assay period is 2 days. | |||
| (Catalog No.: PMC-AK71) | |||
| 4 | Albumin Anti-Glycation Assay Kit Glyceraldehyde |
Glyceraldehyde is added to a BSA (albumin) solution and the saccharification reaction is monitored by fluorescence. | Screening of anti-glycation substances, development of anti-glycation materials in the development of functional foods and cosmetics |
| Assay period is 1 day. | |||
| (Catalog number: CSR-AAS-AGE-K01) | |||
| 5 | Elastin Anti-Glycation Assay Kit Glyceraldehyde |
The saccharification reaction that occurs when glyceraldehyde is added to the elastin solution is monitored by fluorescence. | Screening of anti-glycation substances, research on prevention of lifestyle-related diseases and aging, and development of functional materials focusing on blood vessels and ligaments |
| Assay period is 1 day. | |||
| (Catalog No.: CSR-AAS-AGE-K05) | |||
| 6 | Collagen AGEs anti-glycation assay kit CML-specific |
Detection of saccharification reaction that occurs when glyoxal is added to collagen immobilized on a 96-well plate with a CML-specific antibody (ELISA method) | Screening of CML production inhibitors, development of anti-glycation materials in the development of functional foods and cosmetics |
| (Catalog number: CSR-AAS-AGE-K02) | |||
| 7 | Collagen AGEs anti-glycation assay kit CMA specific |
CMA-specific antibody detection of saccharification reaction that occurs when glyoxal is added to collagen immobilized on a 96-well plate (ELISA method) | Screening of CMA production inhibitors, development of anti-glycation materials in the development of functional foods and cosmetics |
| (Catalog number: CSR-AAS-AGE-K03) | |||
| 8 | RAGE-reactive AGE production inhibition assay kit | Detection of AGEs (Glyceraldehyde-AGEs) generated when albumin immobilized on a 96-well plate is saccharified with glyceraldehyde using recombinant RAGE-Fc | Screening of inhibitors of glyceraldehyde-AGEs production, development of anti-glycation materials in the development of functional foods and cosmetics |
| (Catalog number: CSR-AAS-AGE-K04) | |||