Human Adipose-Derived Mesenchymal Stem Cells

Cellular Engineering Technologies

Catalog No.: CET-CR1004-500

Human Adipose-Derived Mesenchymal Stem Cells (AdMSCs)

Human Adipose-Derived Mesenchymal Stem Cells (AdMSCs) are stem cells isolated from adult human lipoaspirate tissue collected during elective surgical liposuction procedures. These cells exhibit high proliferation capacity, strong differentiation potential, and robust immunomodulatory properties, making them a powerful tool for research and therapeutic applications. Their ability to maintain stability through multiple passages while retaining differentiation capabilities ensures consistent and reliable results in laboratory settings.

AdMSCs have demonstrated significant potential in regenerative medicine, particularly in treating autoimmune [i] and neurodegenerative diseases [ii]. Researchers have reported that these cells can differentiate into multiple lineages, including chondrogenic, osteogenic, adipogenic, and neural cell types. Their adaptability and therapeutic relevance make them a valuable resource for studying cell-based therapies, tissue engineering, and disease modeling.

These cells provide a promising platform for investigating novel treatment strategies, including wound healing, bone and cartilage regeneration, and immune modulation. With their ease of expansion, and ability to secrete bioactive factors that promote tissue repair, AdMSCs are widely used in preclinical and clinical studies. Whether applied in, cell therapy development, or in vitro disease modeling, these cells offer a scalable and reproducible system for  biomedical research.

Product Specifications:

• Source: Human lipoaspirate tissue from elective liposuction procedures
• Multipotency: Capable of differentiating into chondrogenic, osteogenic, adipogenic, and neural lineages
• Applications: Regenerative medicine, tissue engineering, immunotherapy, metabolic disease research, and neurodegenerative disease studies
• Quality Assurance: Screened for viability, sterility, and mycoplasma contamination
• Please contact us for additional donor information.

Recommended Products for Adipose-Derived Mesenchymal Stem Cells:

• Human MSC Expansion Media (CET-MR1016)
• Human Chondrogenic Differentiation Media (CET-MR1008)

Shipping & Storage:

• Vial contains approximately 500,000 cells
• Shipped with dry ice or liquid nitrogen to maintain stability and viability during transport
• Storage recommendation: Store in liquid nitrogen vapor phase for long-term viability

Citations for Human Adipose-Derived Mesenchymal Stem Cells – 15 Found

Yu, Song-Hee; Jang, Yu-Jin; Lee, Eun-Shil; Hwang, Dong-Youn; Jeon, Chang-Jin. Transplantation of adipose derived stromal cells into the developing mouse eye. Acta Histochemica Et Cytochemica. 2010;43(6):123-30. 

Iwata, Takanori; Yamato, Masayuki; Zhang, Zheng; Mukobata, Shigeki; Washio, Kaoru; Ando, Tomohiro; Feijen, Jan; Okano, Teruo; Ishikawa, Isao. Validation of human periodontal ligament-derived cells as a reliable source for cytotherapeutic use. Journal Of Clinical Periodontology. 2010;37(12):1088-99. 

Xie, Jingwei; Ma, Bing; Michael, Praveesuda Lorwattanapongsa. Fabrication of novel 3D nanofiber scaffolds with anisotropic property and regular pores and their potential applications. Advanced Healthcare Materials. 2012;1(5):674-8. 

Wu, Jyun-Yi; Chen, Chia-Hsin; Wang, Chau-Zen; Ho, Mei-Ling; Yeh, Ming-Long; Wang, Yan-Hsiung. Low-power laser irradiation suppresses inflammatory response of human adipose-derived stem cells by modulating intracellular cyclic AMP level and NF-κB activity. Plos One. 8(1):e54067. 

Song, Myeongjin; Jang, Hwanseok; Lee, Jaeyeon; Kim, Ji Hyun; Kim, Soo Hyun; Sun, Kyung; Park, Yongdoo. Regeneration of chronic myocardial infarction by injectable hydrogels containing stem cell homing factor SDF-1 and angiogenic peptide Ac-SDKP. Biomaterials. 2014;35(8):2436-45. 

Wang, Yan-Hsiung; Wu, Jyun-Yi; Chou, Pei-Jung; Chen, Chung-Hwan; Wang, Chau-Zen; Ho, Mei-Ling; Chang, Je-Ken; Yeh, Ming-Long; Chen, Chia-Hsin. Characterization and evaluation of the differentiation ability of human adipose-derived stem cells growing in scaffold-free suspension culture. Cytotherapy. 2014;16(4):485-95. 

Park, Eulsoon; Cho, Hong-Baek; Takimoto, Koichi. Effective gene delivery into adipose-derived stem cells: transfection of cells in suspension with the use of a nuclear localization signal peptide-conjugated polyethylenimine. Cytotherapy. 2015;17(5):536-42. 

Park, Eulsoon; Takimoto, Koichi. A long-lasting cardiomyogenic gene expression by PEI-based transfection induces endogenous cardiac mRNAs in human adipose-derived stem cells. Biochemical And Biophysical Research Communications. 2016;479(1):12-6. 

Maffey, A; Storini, C; Diceglie, C; Martelli, C; Sironi, L; Calzarossa, C; Tonna, N; Lovchik, R; Delamarche, E; Ottobrini, L; Bianco, F. Mesenchymal stem cells from tumor microenvironment favour breast cancer stem cell proliferation, cancerogenic and metastatic potential, via ionotropic purinergic signalling. Scientific Reports. 2017;7(1):13162. 

Wang, Yan-Hsiung; Wu, Jyun-Yi; Kong, Su Chii; Chiang, Min-Hsuan; Ho, Mei-Ling; Yeh, Ming-Long; Chen, Chia-Hsin. Low power laser irradiation and human adipose-derived stem cell treatments promote bone regeneration in critical-sized calvarial defects in rats. Plos One. 13(4):e0195337. 

Park, Eulsoon; Baek, Seung Hwa; Bang, Keuk Su; Kim, Na Hyung; Takimoto, Koichi. Fermented Garlic Extract Increases Oxygen Consumption and UCP-1 mRNA Expression in Human Adipose-Derived Stem Cells. Cell Journal. 2019;21(3):357-362. 

Chu, Kuo-An; Yeh, Chang-Ching; Hsu, Chun-Hsiang; Hsu, Chien-Wei; Kuo, Fu-Hsien; Tsai, Pei-Jiun; Fu, Yu-Show. Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells. International Journal Of Molecular Sciences. 2023;24(8) 

Gong, Yi; Dai, Haisu; Liu, Wei; Liao, Rui; Chen, Hailei; Zhang, Leida; Wang, Xiaojun; Chen, Zhiyu. Exosomes derived from human adipose-derived stem cells alleviate hepatic ischemia-reperfusion (I/R) injury through the miR-183/ALOX5 axis. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2023;37(3):e22782. 

Yu, Hong-Ren; Huang, Hsin-Chun; Chen, I-Lun; Li, Sung-Chou. Exosomes Secreted by Wharton's Jelly-Derived Mesenchymal Stem Cells Promote the Ability of Cell Proliferation and Migration for Keratinocyte. International Journal Of Molecular Sciences. 2024;25(9) 

Yamada, Azusa; Iwata, Takanori; Yamato, Masayuki; Okano, Teruo; Izumi, Yuichi. Diverse functions of secreted frizzled-related proteins in the osteoblastogenesis of human multipotent mesenchymal stromal cells. Biomaterials. 2013;34(13):3270-8.