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Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.
Click here for the Neuroscience Products Dashboard Page.Application: IHC(p), WB, IF
Clonality: Polyclonal
Host: Rabbit
Purification: Serum
Reactivity: Mouse, Rat
Syndecan is the family name of transmembrane proteoglycans that carry predominantly heparan sulfate side chains. This proteoglycan family consists of four members. N-syndecan (syndecan-3) is the principal member expressed during early postnatal development in both central and peripheral nervous systems. N-syndecan binds various heparin-binding growth factors such as FGFs via the heparan sulfate moiety, and communicates with the cytoskeleton via the cytoplasmic domain of the core protein. N-syndecan plays a pivotal role in formation of the neural network through these molecular interactions. This antibody recognizes effectively the core protein of N-syndecan.
References:
1) Watanabe, E., Matsui, F., Keino, H., Ono, K., Kushima, Y., Noda, H.. & Oohira, A., A membrane-bound heparan sulfate proteoglycan that is transiently expressed on growing axons in the rat brain, (1996) J. Neurosci. Res., 44, 84-96.
2) Toba, Y., Horie, M., Sango, K., Takashiki, A., Matsui, F., Oohira, A., & Kawano, H., Expression and immunohistochemical localization of heparan sulfate proteoglycan N-syndecan in the migratory pathway from the rat olfactory placode, (2002) Eur. J. Neurosci., 15, 1-13.
| Documents & Links for Anti N-Syndecan (SDC3) pAb | |
| Datasheet | cac-nu-07-004_anti-n-syndecan-pab_datasheet.pdf |
| Documents & Links for Anti N-Syndecan (SDC3) pAb | |
| Datasheet | cac-nu-07-004_anti-n-syndecan-pab_datasheet.pdf |