Human Panc-1 Cells

Cellular Engineering Technologies

Catalog No.: CET-CR1016-500

Human Panc-1 Pancreatic Cancer Cells

Human Panc-1 Pancreatic Cancer Cells are a well-established human pancreatic cancer cell line derived from a pancreatic ductal adenocarcinoma (PDAC) isolated from a 56-year-old male donor [i]. Moreover, these cells exhibit an epithelial morphology and adhere to standard cell culture surfaces. Thus, Panc-1 cells are widely utilized in cancer research due to their metastatic potential and resistance to differentiation, making them a robust model for studying pancreatic cancer progression, therapeutic interventions, and drug resistance mechanisms.

Panc-1 cells play a crucial role in research on tumor migration, keratin reorganization, and cytoskeletal changes. Therefore, studies have highlighted their involvement in calcium-mediated actin resetting, a key process in cellular adaptation to physiological stress [ii]. Their ability to grow in both 2D and 3D culture systems makes them valuable for cancer research, high-throughput screening, and assay development.  These cells naturally form clumps in culture, but trypsin treatment prevents aggregation [iii].

Human Panc-1 cells provide a reliable and well-characterized model for pancreatic cancer research, offering insights into tumor progression, metastasis, and therapeutic targeting. Their adaptability for both traditional and advanced culture techniques makes them a valuable asset for preclinical and translational research.

Product Specifications

• Source: Pancreatic ductal adenocarcinoma from a 56-year-old male donor
• Cell Type: Human pancreatic cancer epithelial cell line
• Morphology: Adherent, epithelial-like with a tendency to form clumps
• Applications:
  • Pancreatic cancer research and metastasis studies
  • Drug screening and resistance modeling
  • 3D culture and tumor microenvironment studies
  • High-throughput assay development
• Growth Characteristics: Metastatic potential with poor differentiation capacity

Related Products for Human Panc-1 Cells

• Human Panc-1 Expansion Media (CET-MR1012)
• Human Panc-1 Research Starter Kit (CET-BR1002)

Shipping & Storage

• Vial Size: Approximately 500,000 cells
• Shipping Conditions: Shipped on dry ice to maintain viability
• Storage Recommendation: Store in liquid nitrogen vapor phase for long-term preservation

Citations for Human Panc-1 Cells – 1 Found

Feng, Rui; Morine, Yuji; Ikemoto, Tetsuya; Imura, Satoru; Iwahashi, Shuichi; Saito, Yu; Shimada, Mitsuo. Nab-paclitaxel interrupts cancer-stromal interaction through C-X-C motif chemokine 10-mediated interleukin-6 downregulation in vitro. Cancer Science. 2018;109(8):2509-2519.