Anti Organic Anion Transporter 3 / OAT3 (Rat) pAb

Cosmo Bio

SKU: KAL-KE035

To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fall into various transport systems by the transportative substrate. In particular, oraganic ion transporter family is comprised of organic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of both endogeneous and exogeneous anions. Rat organic anion transporter 3 (OAT3) encodes a 536 amino acid residue protein, of which molecular weight is 130kDa. OAT3 is expressed in the kidney, liver, brain, and eye. OAT3 mediated the uptake of organic anions, such as PAH (-aminohippurate), ochratoxin A and estrone sulfate, cimetidine, and prostaglandin E2. This antidody has been proved to be useful for immunohistochemistry.

Product Specifications

• Application: IHC
• Reactivity: Rat
• Clonality: Polyclonal
• Host: Rabbit

Citations for Anti Organic Anion Transporter 3 / OAT3 (Rat) pAb – 1 Found

Thongnak, Laongdao; Chatsudthipong, Varanuj; Lungkaphin, Anusorn. Mitigation of renal inflammation and endoplasmic reticulum stress by vildagliptin and statins in high-fat high-fructose diet-induced insulin resistance and renal injury in rats. Biochimica Et Biophysica Acta. Molecular And Cell Biology Of Lipids. 2020;1865(9):158755.