Anti IP6K1 pAb (ATL-HPA040825)

Atlas Antibodies

Catalog No.: ATL-HPA040825-25

Protein Description: inositol hexakisphosphate kinase 1
Gene Name: IP6K1
Alternative Gene Name: IHPK1, KIAA0263
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032594: 97%, ENSRNOG00000019932: 96%
Entrez Gene ID: 9807
Uniprot ID: Q92551
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: DSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSP
• Gene Sequence: DSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSP
• Gene ID - Mouse: ENSMUSG00000032594
• Gene ID - Rat: ENSRNOG00000019932
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti IP6K1 pAb (ATL-HPA040825) – 9 Found

Jadav, Rathan S; Kumar, Dharmika; Buwa, Natasha; Ganguli, Shubhra; Thampatty, Sitalakshmi R; Balasubramanian, Nagaraj; Bhandari, Rashna. Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice. Cellular Signalling. 2016;28(8):1124-36. 

Fu, Chenglai; Rojas, Tomas; Chin, Alfred C; Cheng, Weiwei; Bernstein, Isaac A; Albacarys, Lauren K; Wright, William W; Snyder, Solomon H. Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1. Scientific Reports. 2018;8(1):7039. 

Wilson, Miranda S; Jessen, Henning J; Saiardi, Adolfo. The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export. The Journal Of Biological Chemistry. 2019;294(30):11597-11608. 

Jadav, Rathan S; Chanduri, Manasa V L; Sengupta, Sagar; Bhandari, Rashna. Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair. The Journal Of Biological Chemistry. 2013;288(5):3312-21. 

Gu, Chunfang; Wilson, Miranda S C; Jessen, Henning J; Saiardi, Adolfo; Shears, Stephen B. Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels. Plos One. 11(10):e0165286. 

Rajasekaran, Subu Surendran; Illies, Christopher; Shears, Stephen B; Wang, Huanchen; Ayala, Thais S; Martins, Joilson O; Daré, Elisabetta; Berggren, Per-Olof; Barker, Christopher J. Protein kinase- and lipase inhibitors of inositide metabolism deplete IP(7) indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity. Cellular Signalling. 2018;42( 29042286):127-133. 

Sahu, Soumyadip; Wang, Zhenzhen; Jiao, Xinfu; Gu, Chunfang; Jork, Nikolaus; Wittwer, Christopher; Li, Xingyao; Hostachy, Sarah; Fiedler, Dorothea; Wang, Huanchen; Jessen, Henning J; Kiledjian, Megerditch; Shears, Stephen B. InsP(7) is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2020;117(32):19245-19253. 

Sandström, Josefine; Balian, Alien; Lockowandt, Rebecca; Fornander, Tommy; Nordenskjöld, Bo; Lindström, Linda; Pérez-Tenorio, Gizeh; Stål, Olle. IP6K2 predicts favorable clinical outcome of primary breast cancer. Molecular And Clinical Oncology. 2021;14(5):94. 

Ito, Masatoshi; Fujii, Natsuko; Kohara, Saori; Hori, Shuho; Tanaka, Masayuki; Wittwer, Christopher; Kikuchi, Kenta; Iijima, Takatoshi; Kakimoto, Yu; Hirabayashi, Kenichi; Kurotaki, Daisuke; Jessen, Henning J; Saiardi, Adolfo; Nagata, Eiichiro. Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP(7) metabolism in the enteric nervous system. The Journal Of Biological Chemistry. 2023;299(3):102928.