Quantity: 100 µL/vial (1 mg/mL) Clone: EMR8-5 Isotype: IgG1 Buffer: Phosphate buffered saline pH7.4, 0.05% Sodium Azide Immunogen: recombinant HLA-A*2402 extracellular domain Specificity: Heavy chains of HLA-A, HLA-B, HLA-C Applications: Immunohistochemistry (formalin-fixed tissue, 1:50 ~ 1:100) Western blotting Storage: Store at 2 ~ 8°C. For long-term storage aliquot and store at -20°C. Avoid freeze / thaw cycles.
References:
1. Torigoe T, Asanuma H, Shimozawa K, et al. Immunohistochemical analysis of HLA class I expression in tumor tissues revealed unusually high frequency of down-regulation in breast cancer tissues. J. Translational Med. Submitted
2. Komori H, Nakatsura T, Senju S, Yoshitake Y, Motomura Y, Beppu T, Matsui M, Torigoe T, Sato N, Baba H, Nishimura Y. Identification of HLA-A2 or -A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy for hepatocellular carcinoma. Clinical Cancer Res. 12, 2689-2699 (2006)
3. Kitamura H, Torigoe T, Sato N, et. al, Expression and antigenecity of surviving, and inhibitor of apotosis family member, in bladder cancer: implications for specific immunotherapy. J Urology Submitted. 67, 955-959 (2006)
Product Specifications
Application
IHC, WB
Reactivity
Human
Clonality
Monoclonal (Clone No.: EMR8-5)
Host
Mouse
Documents & Links for Anti HLA Class I-A, B, C mAb (Clone EMR8-5)