RuvC protein

Cosmo Bio LTD

Catalog No: BAM-01-011-EX

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Applications: Studies on homologous recombination mechanism

To use as endonuclease which functions specifically to the Holliday structure E. coli RuvC protein is a structurally specific endonuclease which binds specifically to the Holliday structure, an intermediate of recombination, at the late stage of homologous recombination and recombination repair and introduces a nick in the symmetrical point of the Holliday junction cleaving and resolving the recombinant (1, 2). The product is a recombinant protein abundantly expressed by E. coli and purified by methods such as chromatography (Fig. 1). Its molecular weightis19 kD and Forms a dimer in liquid and in binding tate with the Holliday structure.