Anti Tetanus Toxin mAb (Clone TH-11)

Cosmo Bio LTD

Catalog No: BAM-64-035-EX

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Application: ELISA, WB, Neutralization 
Clonality: Monoclonal 
Host: Mouse 
Purification: IgG 
Reactivity: Clostridium tetani 
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the

axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. Application: 1. Western blotting (1/1,000 dilution)

2. ELISA (assaydependent)

3. Neutralising of the toxin activity (assay dependent)

Other applications have not been tested.